Cephalosporins Part 2

Question 1

3rd Gen Ceph

Answer 1

Ceftriaxone, cefotaxime, ceftazidime, cefdinir, cefpodoxime

Question 2

3rd Gen Ceph Spectrum

Answer 2

Good: strept, enteric GNRs, Pseudomonas (ceftazidime only)
Mod: MSSA (not ceftazidime)

Question 3

Ceftriaxone Dose

Answer 3

IV/IM: 1-2 g q12-24h; no renal

Question 4

Cefotaxime Dose

Answer 4

IV/IM: 1-2 g q4-12h

Question 5

Cefotaxime Renal

Answer 5

0-20: half

Question 6

Cefdinir Dose

Answer 6

PO: 300 mg BID or 600 mg Daily

Question 7

Cefdinir Renal

Answer 7

0-30: 300 mg daily

Question 8

Ceftriaxone Cautions

Answer 8

Crystallizes with calcium, biliary sludging in neonates

Question 9

Cefpodoxime Dosing

Answer 9

PO: 100-400 mg q12h

Question 10

Cefpodoxime Renal

Answer 10

0-30: q24h

Question 11

Ceftazidime Dosing`

Answer 11

IV/IM: 1-2 g q8h

Question 12

Ceftazidime Renal

Answer 12

31-50: 2 g q12h, 16-30: 1 g q12h, 6-15: 1 q24h, 0-5: 500 mg q24h

Question 13

Ceftaroline Spectrum

Answer 13

Good: MSSA, MRSA, strepto, enteric GNRS
Mod: E. faecalis

Question 14

Ceftaroline Dosing

Answer 14

IV: 600 mg q12h

Question 15

Ceftaroline Renal

Answer 15

31-50: 400 mg, 15-30: 300 mg, 0-15: 200 mg

Question 16

Cefepime

Answer 16

Good: MSSA, strept, Pseudomonas, enteric GNRs
Mod: Acinetobacter

Question 17

Cefepime Dose

Answer 17

IV/IM: 1-2 g q8-12h

Question 18

Cefepime Renal

Answer 18

30-60: 2 g q12h, 11-29: 2g q24h, 0-11: 1 gm q24h