Pencillins

Question 1

What are the four classes of penicillins?

Answer 1

1. Natural Penicillins
2. Aminopenicillins
3. Extended Spectrum
4. Staph-Resistant

Question 2

What are the natural penicillins effective against?

Answer 2

Gram + organisms: Group A Strep, Strep Pneumo

Question 3

How is penicillin V given?

Answer 3

PO

Question 4

How is penicillin G given?

Answer 4

IM

Question 5

Penicillin G is used to treat which UTI?

Answer 5

syphillis

Question 6

What is the mechanism of action of the natural penicillins?

Answer 6

Inhibit cell wall synthesis

Question 7

Are the natural penicillins bacteriostatic or bactericidal?

Answer 7

bactericidal

Question 8

What type of hypersensitivity reaction can occur with penicillins?

Answer 8

Type 1

Question 9

Describe the absorption of Penicillin V:

Answer 9

Adequate PO absorption. can cause GI symptoms

Question 10

Describe the absorption of penicillin G:

Answer 10

IM. long half-life

Question 11

Patient education regarding Penicillin V & food?

Answer 11

Should be taken on an empty stomach as food can delay absorption. 1 hour before a meal, or 2 hours after

Question 12

Monitoring recommended when using penicillin G:

Answer 12

BUN/Creat & Potassium

Question 13

What lab should be monitored in patients taking Amoxicillin/Clavulanate?

Answer 13

BUN & Creat

Question 14

What is the mechanism of action for Amoxicillin/Clavulanate?

Answer 14

Inhibition of cell wall synthesis

Question 15

What is Amoxicillin/Clavulanate used to treat?

Answer 15

Respiratory infections, skin infections

Question 16

Do penicillins cross the placenta & breast milk?

Answer 16

Yes

Question 17

What are the indications for amoxicillin?

Answer 17

CAP, Otitis media, Lyme disease, Chronic bronchitis

Question 18

What are the indications for amoxicillin?

Answer 18

CAP, Otitis media, Lyme disease, Chronic bronchitis

Question 19

Considerations for amoxicillin/clavulanate

Answer 19

Renal function
Hepatic dysfunction during prolonged therapy