Pediatrics Recall Flashcards
Olive shaped mass
Pyloric stenosis
“Shoulder Sign” and “Double Tract Sign” on Barium Swallow
Pyloric stenosis
Surgical Procedure of Pyloric Stenosis
Ramstedt Pyloromyotomy
Birds Beak Sign
Volvulus
Inverted U Sign
Volvulus
Coffee Bean Sign
Volvulus
Failure to recanilize the lumen
Duodenal Atresia
Obstruction usually distal to the ampulla of vater
Duodenal Atresia
Bilious vomiting without abdominal distention usually noted on the 1st day of life
Duodenal Atresia
Double Bubble Sign
Duodenal Atresia
Surgical Tx of Duodenal Atresia
Duodenoduodenostomy with gastrotomy tube
Pg18 TN
Incomplete rotation of the intestine during fetal development
Malrotation
Most common type involve failure of the cecum to move into the RLQ
Malrotation
Remnant of the Omphalomesenteric duct
Meckel Diverticulum
Intermittent painless rectal bleeding and “Brick colored stool”
Meckel Diverticulum
Congenital Aganglionic Megacolon
Hirschprung Disease
Most common cause of lower intestinal obstruction in neonates;
M > F
Hirschprung Disease
Absence of ganglionic cells in the bowel wall beginning in the “Internal Anal Sphincter”
Hirschprung Disease
Absence of Meisnner and Auerbach plexus
Hirschprung Disease
Begins at birth with the Delayed Passage of Meconium
Hirschprung Disease
Pellet or Ribbon like stool
Hirschprung Disease
Currarino Triad
Hirschprung Disease
Pg19 TN
Sausage-shaped mass in the RUQ which may inc in size and firmness during a paroxysm of pain
Intussusception
Barium enema: “Coiled Spring Sign”
Intussusception
UTZ: Doughnut or Target Sign
Intussusception
Most common cause of non bilious vomiting
Pyloric stenosis
More specific for acute inflammatory pancreatic disease
Serum lipase
Abd Xray: Sentinel loop
Acute Pancreatitis
Abd Xray: Cutoff Sign: dilated transverse colon
Acute Pancreatitis
Abd Xray: Blurring of left psoas margin
Acute Pancreatitis
Severe flank pain radiating to the groin
Renal Colic from Calculi
Sudden onset offross or microscopic hematuria and unilateral or bilateral flank mass
Renal Vein Thrombosis
Gross hematuria, Periorbital edema, Hypertension, Oliguria
Acute PostStreptococcal Gromerulonephritis
Most common chronic glomerular disease worldwide
IgA Nephropathy
Bilateral flank pain masses during the neonatal period or early infancy
Polycystic Kidney Disease
Associated with Potter Facies
Polycystic Kidney Disease
Renal UTZ: enlarged and hyperechogenic kidneys with poor corticomedullary distinction
Potter Syndrome
Most common cause of acute renal failure in young adults
Hemolytic Uremic Syndrome
Pg27 TN
Microangiopathic Hemolytic Anemia
Hemolytic Uremic Syndrome
Pg27 TN
Precedes more than 80% of HUS in devolped countries
Shiga toxin producing Escherichia coli 0157:H7
Peripheral Smear: Helmet cells
Hemolytic Uremic Syndrome
Pg27 TN
Peripheral smear: Burr cells
Hemolytic Uremic Syndrome
Pg27 TN
Peripheral smear: Fragmented RBCs
Hemolytic Uremic Syndrome
Pg27 TN
Upper limit of normal protein excretion in healthy children
150mg/day
T-cells first detected in the thymus
7th - 8th week of gestation
Pg29 TN
Vital organ for immune response to blood borne antigens
Spleen
Mucosa Associated Lymphoid Tissue (MALT)
Pe yer’s patch in the lamina propria of the SI
L ymphoid follicles in the appendix
T onsils in the pharynx
S ubmucosal lymphoid tissue throughout the upper airways & bronchi
A protein that creates pores on cell membranes of target cells resulting in lysis
Cytolysin
First line of defense against neonatal herpes virus infection
Natural Killer Cells
Functions of Phagocytes
Diapedesis
Chemotaxis
Phagocytosis
Killing
Main anaphylatoxins that provokes inflammation
C3a and C5a
Role in opsonization
C3b and C5b
B Cell Deficiency: deficiency of tyrosine kinase that blocks B cell maturation
Bruton’s X-linked Agammaglobulinemia
B Cell Deficiency: deficiency of CD40L on activated T cell
X Linked Hyper IgM Syndrome
B Cell deficiency: most common IgA defiency
Selective IgA Deficiency
B Cell Deficiency: Delayed onset of maturation of normal IgG
Transient Agammaglobulinemia
T Cell Deficiency: Thymic hypoplasia and T cell specific
DiGeorge Syndrome
T Cell Deficiency: defective cytoskeletal gylycoprotein
Wiskott Aldrich
Most common T Cell Deficiency
Severe Combined Immunodeficiency
Adenosine Deaminase Deficiency
Severe Combined Immunodeficiency
Defects in Phagocytosis: Deficiency in NADPH oxidase and recurrent infxn with Catalase +
Chronic Granulomatosis Disease
Defects in Phagocytosis: absence of CD18
Leukocyte Adhesion Defect
Defects in Phagocytosis: Delayed in umbilical cord sloughing
Leukocyte Adhesion Defect
Defects in Phagocytosis: Granule structure defect
Chediak-Hegashi Syndrome
Defects in Phagocytosis: Recurrent bacterial infxn and partial albinism
Chediak-Higashi Syndrome
Defects in Phagocytosis: Deficiency in enzyme needed in HMP
Glucose 6 Phosphate Deficiency
Defects in Phagocytosis: Hemolytic Crisis
Glucose 6 Phosphate Deficiency
Defects in Phagocytosis: Granule ENZYME deficiency
Myeloperoxidase Deficiency
Defects in Phagocytosis: Deficiency in TNF-gamma
Job’s Syndrome
Defects in Complement: Deficiency in regulatory of protein
Hereditary Angioedema
Screening Test for Macrophage Deficiency
Nitroblue Tetrazolium Test
Respiratory Burst Assay
Screening Test for Complement Deficiency
CH50
Rachitic Rosary
Rickets
Harrison Groove
Rickets
Valgus deformity of 1 leg with Varus deformity of the other leg
Windswept Deformity
Rickets
Angular Cheilosis
Perleche
Magenta Tongue
Glossitis
Dermatitis, Diarrhea, Dementia and Death
Pellagra
Pellagra
Niacin Deficiency
Vit. B3
Microcytic Anemia
Vit B6 Deficiency
Megaloblastic Anemia
Vitamin B12 deficiency
Scorbutic Rosary
Scurvy
Corckscrew Hair
Scurvy
Inadequate CALORIC intake + non-edematous
Marasmus
Starvation type of diarrhea
Marasmus
Insufficient intake of PROTEIN of good biologic value
Kwashirkor
Streaky red or grey hair in dark-haired children
Hypochromotrichia
Kwashirkor
Extreme Exogenous Obesity
Pickwickian Syndrome
Severe cardiorespiratory distress with alveolar hypoventilation
Pickwickian Syndrome
Most severe form of neural tube defect (Dysraphism)
Meningocele
Failure of the neural tube to close spontaneously between the 3rd and 4th wk in utero
Meningocele
Due to failure of closure of the ROSTRAL NEUROPORE
Anencephaly
Absent cerebral hemisphere and cerebellum with a residue of brainstem
Anencephaly
Absent cerebral convolutions and poor formed sylvian fissure
Lissencephaly (Agyria)
Faulty neuroblast migration
Lissencephaly (Agyria)
Unilateral or bilateral clefts within the cerebral hemispheres
Schizencephaly
Presence of cysts or cavities within the brain
Porencephaly
Develop during perinatal/postnatal period due to problems of arterial or venous circulation
Pseudoporencephalic cysts
Defective cleavage of the prosencephalon and inadequate induction of the forebrain structures
Holoprosencephaly
Impaired circulation and absorption of CSF from increase production of CSF
Hydrocephalus
Obstruction within the ventricular system
Obstructive or Non-communicating type of Hydrocephalus