pediatric Flashcards
what Ig in milk vs placenta
IgA milk
IgG placenta cross
child bolus
20 cc/kg
child transfusion
10 cc/kg
tachycardia in child
neonate > 150
1 yr > 120
otherwise > 100
UOP child goal
2-4 cc/kg/hrc
congenital cystic disease of lung causes
- pulmonary sequestration from anomalous systemic arterial supply (aorta via pulmonary ligament) and drainage thru azygous vs pulmonary vein… need to ligate arterial supply then lobectomy (can bleed)
- lobar overinflation/emphysema from cartilage failure in bronchus (air trap) (can cause tPTX) mostly LUL… lobectomy
- cystic adenoid malformation CCAM communciated with airway causing resp compromise/infection… lobectomy
bronchiogenic cyst mgmt
resect, malignant potential
bronchiogenic cyst location
mediastinum; posterior to carina; filled with milky
LAD unknown
10 days antibiotics suspect from infection
then excisional bx (to r/o lymphoma)
cystic hygroma LYMPHANGIOMA
found in lateral cervical POSTERIOR regions in neck; gets infected & multiloculated…… lateral to the SCM muscle
can connect to IJ
RESECT!
congenital diaphragmatic hernia
sx: both lungs dysf(x)l, hypoplastic and pulm HTN
mgmt diaph hernia
high freq ventilation, inhaled NO, ECMO
look for anomalies (cardiac, neural tube defects, malro)
bochdalek’s hernia
mC diaph hernia… located posteriorly
morgagni hernia
rare diaph hernia… located anteriorly
pectus excavatum
sinks in…
mgmt: sternal osteotomy with strut= Nuss or Ravitch procedure
pectus carinatum
pushes out…
mgmt: repair if emotional stress
1st branchial cyst
angle of mandible; poss connect to external auditory canal
ass’d with facial nerve
tx: resect
2nd branchial cyst MCMCMCMCMCMCM
MC**
anterior border of mid-SCM muscle
thru carotid bifurc into tonsillar pillar
tx: resect
3rd branchial cyst
lower neck, MEDIAL to/lower SCM to the piriform sinus
tx: resect
thyroglossal duct cyst
MIDLINE.
goes thru hyoid bone;descends thru foramen cecum
mgmt: excise cyst, tract, hyoid (at least central portion) = SISTRUNK POCEDURE
hemangiomas in kids
usually involte after 1YO… resolve at 7-8 YO
can resect after steroids if uncontrollable growth/impairs function
sx of neuroblastoma (MC abd malignancy solid in children)
secretory diarrhea, raccoon eyes (orbital met), HTN, opsomy-oclonus syndrome (unstead)
usually < 2 YO (Wilms older)
mgmt neuroblastoma
resect adrenal and kidney
if uresectable, doxorubicin chemo…need tissue dx first (n-myc vs no mutation) will change chemo
poor Px: neuron specific enolase, LDH, HVA, diploid, MYCN amplification
neuroblastoma staging
I: excised
II: incomplete excision does not cross midline
III: crosses midline +/- nodes
IV distant mets
wilms tumor = nephroblastoma
3 YO dx
prognosis wilms tumor based on?
GRADE LIKE SARCOMAS
wilms met to?
bone. &. LUNG (whole lung XRT)
sx wilms
asx»_space;» hematuria, HTN (mostly unilateral
mgmt wilms
nephrectomy withotu rupture
pull tumor out of renal vein
and LN SAMPLING*
stage II+ (not fully resected) needs actinomycin and vincristine
wilms staging
I; limited to kidney, excised
II: beyodn kidney but excied
III: residual nonhematogenous tumor
IV: heme mets
V: b/l renal involvement (needs nephron sparing surgery)
bone & lung mets need RADIATION
hepatoblastoma
AFP**
b-hCG release: fractures, precocious puberty
<3 YO
beckwith wiedemann syndrome
ass’d with hepatoblastoma and Wilms
mgmt hepatoblastoma
resect
doxorubicin if unresectable
plastinum chemotherapy if positive margin and then watch & wait
best prognosis for hepatoblastoma
FETAL HISTOLOGY
MC chid malignancy overall
ALL
MC solid tumor classs
CNS tumors
MC cause of duo obstruction <1wk old
duodenal atresia