PCOS Flashcards

1
Q

What are features of PCOS?

A

Subfertility/infertility
Menstrual disturbances- oligomenorrhoea/amenorrhoea
Hirsutism e.g. acne
Obesity
Acanthosis Nigricans

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2
Q

What investigations are required?

A

Pelvic USS- multiple cysts
Prolactin- normal/mildly elevated
LH:FSH- can be raised
Testosterone- normal/raised
Sex hormone Binding globulin- low
Check for impaired glucose tolerance

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3
Q

How is it diagnosed?

A

Rotterdam Criteria
2 of 3 present
1) Infrequent or no ovulation
2) Clinical or biochemical signs of hyperandrogenism
3) Polycystic ovaries in one or both ovaries >12 follicles

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4
Q

What is the management?

A

Weight loss
COCP can be good for acne/regulating cycle

Fertility
- specialist review
- clomifene can be good
- Metformin second line

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