Pathophysiology of Pain

Question 1

what does pain change in the animal’s physiology and behavior to do?

Answer 1

reduce or avoid the damage
reduce likelihood of its recurrence
promote recovery

Question 2

what is nociception?

Answer 2

noxious/harmful stimuli are encoded by the peripheral nervous system and transmitted to the CNS (spinal cord and brain)

Question 3

what are the types of noxious stimuli?

Answer 3

mechanical
chemical
thermal

Question 4

what are the primary sensory neurons?

Answer 4

Abeta
Adelta
C

Question 5

what do primary afferents do?

Answer 5

carry message from periphery to dorsal horn of spinal cord

Question 6

where does serotonin act on the second order neuron?

Answer 6

reticular formation
raphe nucleus magnus

Question 7

where do second-order neurons synapse?

Answer 7

thalamus

Question 8

what happens in primary hyperalgesia?

Answer 8

decreases threshold
increases frequency response
decreases in response latency
spontaneous firing

Question 9

what types of pain cause central sensitization?

Answer 9

chronic pain
neuropathic pain

Question 10

what does neuropathic pain arise from?

Answer 10

injury to peripheral or central nervous system tissues