Pathology of Ischemic CV Disease Flashcards
What are the 3 parts of Virchow’s Triad?
- endothelial injury
- abnormal blood flow
- hypercoagulability
In what layer of the BV does an atheroma develop?
the intima
What are the complications of an aneurism?
- extravasation of blood –> hematoma
2. tear in intima –> dissection
Aortic dissection most commonly occurs with underlying ______.
HTN
What is a double-barreled aorta?
when the aortic intima is torn twice, allowing blood return into the lumen
What are the s/s of an aortic dissection?
sudden, excruciating pain that radiates to the back
What is a Type A aortic dissection?
involves the ascending aorta
What is a Type B aortic dissection?
dissections beyond the takeoff of the great vessels
What is an aortic dissection beyond the takeoff of the great vessels?
a type B aortic dissection
What aortic dissection involves the ascending aorta?
a type A aortic dissection
Is a type A or B aortic dissection worse? Why?
type A – it can travel down into the coronary arteries
How is atherosclerosis ID’d?
fibrofatty plaques on the intima
What is Mönckeberg’s medial calcific sclerosis?
Calcification of media of muscular arteries that does not encroach on vessel lumen
What is the most common aortic aneurism?
abdominal
What is intermittent chest pain caused by reversible
myocardial ischemia?
angina pectoris
What is angina pectoris?
Intermittent chest pain caused by reversible myocardial ischemia
What is Prinzmetal’s (variant) angina?
chest pain that occurs at rest/during sleep due to vasospasm
What is chest pain that occurs at rest/during sleep due to vasospasm called?
Prinzmetal’s (variant) angina
If you have R dominant circulation, like most people, the _____ supplies the _____.
RCA; posterior L ventricle
If you have ______, like most people, the RCA supplies the posterior L ventricle.
R dominant circulation
If you have _____, the L circumflex coronary artery branches supply the posterior L ventricle.
L dominant circulation
If you have L dominant circulation, the ______ branches supply the _______.
L circumflex coronary artery; posterior L ventricle
