Pathology of Ischemic CV Disease

Question 1

What are the 3 parts of Virchow’s Triad?

Answer 1

1. endothelial injury
2. abnormal blood flow
3. hypercoagulability

Question 2

In what layer of the BV does an atheroma develop?

Answer 2

the intima

Question 3

What are the complications of an aneurism?

Answer 3

1. extravasation of blood –> hematoma

2. tear in intima –> dissection

Question 4

Aortic dissection most commonly occurs with underlying ______.

Answer 4

HTN

Question 5

What is a double-barreled aorta?

Answer 5

when the aortic intima is torn twice, allowing blood return into the lumen

Question 6

What are the s/s of an aortic dissection?

Answer 6

sudden, excruciating pain that radiates to the back

Question 7

What is a Type A aortic dissection?

Answer 7

involves the ascending aorta

Question 8

What is a Type B aortic dissection?

Answer 8

dissections beyond the takeoff of the great vessels

Question 9

What is an aortic dissection beyond the takeoff of the great vessels?

Answer 9

a type B aortic dissection

Question 10

What aortic dissection involves the ascending aorta?

Answer 10

a type A aortic dissection

Question 11

Is a type A or B aortic dissection worse? Why?

Answer 11

type A – it can travel down into the coronary arteries

Question 12

How is atherosclerosis ID’d?

Answer 12

fibrofatty plaques on the intima

Question 13

What is Mönckeberg’s medial calcific sclerosis?

Answer 13

Calcification of media of muscular arteries that does not encroach on vessel lumen

Question 14

What is the most common aortic aneurism?

Answer 14

abdominal

Question 15

What is intermittent chest pain caused by reversible

myocardial ischemia?

Answer 15

angina pectoris

Question 16

What is angina pectoris?

Answer 16

Intermittent chest pain caused by reversible myocardial ischemia

Question 17

What is Prinzmetal’s (variant) angina?

Answer 17

chest pain that occurs at rest/during sleep due to vasospasm

Question 18

What is chest pain that occurs at rest/during sleep due to vasospasm called?

Answer 18

Prinzmetal’s (variant) angina

Question 19

If you have R dominant circulation, like most people, the _____ supplies the _____.

Answer 19

RCA; posterior L ventricle

Question 20

If you have ______, like most people, the RCA supplies the posterior L ventricle.

Answer 20

R dominant circulation

Question 21

If you have _____, the L circumflex coronary artery branches supply the posterior L ventricle.

Answer 21

L dominant circulation

Question 22

If you have L dominant circulation, the ______ branches supply the _______.

Answer 22

L circumflex coronary artery; posterior L ventricle