Inflammation and Atherogenesis Flashcards
Dendritic cell antigen presentation with subsequent T
cell activation promotes _____.
clonal T cell expansion
_____ with subsequent T cell activation promotes clonal T cell expansion.
Dendritic cell antigen presentation
Dendritic cell antigen presentation with subsequent _____ promotes clonal T cell expansion.
T cell activation
____ response promotes IFN-gamma elaboration and atherosclerosis.
Th1
Th1 response promotes _____ elaboration and atherosclerosis.
IFN-gamma
Th1 response promotes IFN-gamma elaboration and ______.
atherosclerosis
_____ cells may promote plaque instability and neoangiogenesis.
TH17
TH17 cells may promote _____ and neoangiogenesis.
plaque instability
TH17 cells may promote plaque instability and ______.
neoangiogenesis
Immune response to injury initiates ______.
atherogenesis
_____ interaction with endothelium drives initial plaque formation.
Innate immune cell
_____ promote further lesion expansion and plaque vulnerability.
T cells
_____ degrade the fibrous cap.
Matrix metalloproteinases
Levels of ___ predict increased CV risk. Statins lower both cholesterol and _____.
CRP (both)
Multiple studies have shown an association between
_____ and myocardial infarction.
psoriasis
