Cardiac Embryonic-Fetal Circulation Flashcards
What does the 1st aortic arch become?
disappears- maxillary and ext carotids
When do the tubes fuse together? Why?
day 21-22; the embryo folds cephalically and laterally
When do the great arteries develop?
days 35-56
What does the R cardinal vein become?
SVC brachiocephalic vein innominate veins
The ______ comes from the aortic sac and the ______ comes from the left dorsal.
ascending aorta; descending aorta
What are the 3 looping stages?
- pre-loop 2. loop 3. post-loop
What does the 2nd aortic arch become?
disappears- stapedial a
What does the 6th aortic arch become?
pulmonary a’s ductus arteriosus
The bulbis cordis becomes the _______.
trabeculated portion of the RV
Between the inner and outer layer of the heart tube is a substance called “cardiac jelly” which plays a role in _______.
the looping of the heart as well as septation
The ascending aorta comes from the _____ and the descending aorta comes from the _______.
aortic sac; left dorsal
The _____ will become the intraventricular septum.
Atrioventricular Sulcus
Where does the umbilical vein originate?
the placenta
Epiblast cells migrate through the primitive streak, giving rise to the ______.
intraembryonic mesoderm
The ______ becomes the aortic and pulmonary valves, the ascending aorta, and the pulmonary trunk.
truncus
What are the 3 components of a blastocyst?
- trophoblast (outer cell mass) 2. embryoblast (inner cell mass) 3. blastocyst cavity (central cavity)
What does the 3rd aortic arch become?
carotid a’s
What does the R vitelline vein become?
superior mesenteric a IVC hepatic sinusoids
What does the L cardinal vein become?
ligament of Marshall
The 2 layers of the embryoblast form a flat disc, called the _____.
embryonic disc
The sinus venosus communicates with the primitive atria via the ______.
sinoatrial orifice
What does the 5th aortic arch become?
disappears
What does the L vitelline vein become?
hepatic sinusoids
The truncus becomes the _____.
aortic and pulmonary valves the ascending aorta the pulmonary trunk
On what day does the heart begin to beat?
day 22
What does the R umbilical vein become?
it disappears
At the blastocyst stage, the precardiac cells are located ______ on either side of the _____.
within the epiblast; primitive streak
Where does the cardinal vein originate?
it drains the embryo
Between the inner and outer layer of the heart tube is a substance called “cardiac jelly” which plays a role in _______.
the looping of the heart as well as septation
What does the R sinus horn become?
it’s absorbed into the RA
Zygote –> Morula –> ______
Blastocyst
______ cells migrate through the primitive streak, giving rise to the intraembryonic mesoderm.
Epiblast
The _____ become the L and R atrial appendages.
primitive atria
At day 16, the cells that will become the CV system are in the ______ and are derived from _____.
cardiogenic area; mesodermal cells
The Atrioventricular Sulcus will become the ______.
intraventricular septum
______ –> Morula –> Blastocyst
Zygote
What are the 3 layers of the gastrula?
- ectoderm (external) 2. mesoderm (middle) 3. endoderm (internal)
The proximal portion of the ______ is the primordium of the trabeculated portion of the RV.
Bulbus Cordis
Zygote –> ______ –> Blastocyst
morula
What does the L umbilical vein become?
the ductus venosus, which will disappear after birth
Between the inner and outer layer of the heart tube is a substance called ______ which plays a role in the looping of the heart as well as septation.
“cardiac jelly”
The ______ becomes the infundibula of both ventricles.
conus
What does the 6th aortic arch become?
pulmonary a’s ductus arteriosus
What surrounds the heart tubes at day 19?
splanchnic mesoderm
What happens at day 19?
cardiogenic cells migrate and begin to form 2 endocardial tubes
The ______ communicates with the primitive atria via the sinoatrial orifice.
sinus venosus
The ______ becomes the trabeculated portion of the RV.
bulbis cordis
Where does the Vitelline vein originate?
the yolk sac
When do the atria and ventricles septate?
days 28-42
The primitive ventricle becomes the _____.
trabeculated portion of the LV
The precardiac cells are located within the ______ but then migrate cephalically.
mesoderm
The proximal portion of the Bulbus Cordis is the primordium of the ______ of the RV.
trabeculated portion
The conus becomes the _______.
infundibula of both ventricles
The primitive atria become the _______.
L and R atrial appendages.
What does the L sinus horn become?
ligament of Marshall coronary sinus
The ______ is the primordium of the trabeculated portion of the LV.
Primitive Ventricle
What does the 4th aortic arch become?
R= R brachiocephalic a, R subclavian a L= transverse aortic arch
The sinus venosus communicates with the primitive atria via the ______.
sinoatrial orifice
Epiblast cells migrate through the primitive streak, giving rise to the ______.
intraembryonic mesoderm
The Primitive Ventricle is the primordium of the _____ of the LV.
trabeculated portion
The ______ becomes the trabeculated portion of the LV.
primitive ventricle
The ascending aorta comes from the _____ and the descending aorta comes from the _______.
aortic sac; left dorsal
On what day do the cardiogenic cells migrate and begin to form 2 endocardial tubes?
day 19
Which direction do the primitive atria rotate?
posteriorly
Where does the cardinal vein originate?
the embryo (to drain it)
At _____, the cells that will become the CV system are in the cardiogenic area and are derived from mesodermal cells.
day 16
What are the 2 layers of the embryoblast?
- epiblast (external layer) 2. hypoblast (internal layer)
