Pathology Buzz Words Flashcards by Zak Reneau

Q

GNAS mutation

A

Pituitary adenoma

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Q

PAS+, POMC+

A

Corticotroph adenoma

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Q

Machine oil

A

Adamantinomatous Craniopharyngioma

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Q

Cyclin D1, MEN1 mutations

A

Sporadic Parathyroid Adenoma

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Q

MEN1, RET mutations

A

Familial parathyroid adenoma

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Q

PTHrP

A

Hypercalcemia of Malignancy

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Q

Chronic mucocutaneous candidiasis

A

Autoimmune cause of hypoparathyroidism

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Q

Primary adrenal insufficiency

A

Autoimmune cause of hypoparathyroidism

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Q

APS1

A

Autoimmune cause of hypoparathyroidism

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Q

Inherited hypoparathyroidism

A

GofF CASR, AD

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Q

Familial hypocalciuric hypercalcemia

A

CASR mutation, AD

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Q

Anti-microsomal Ab

A

Hashimoto thyroiditis

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Q

Anti-thyroid peroxidase Ab

A

Hashimoto thyroiditis

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Q

Anti-thyroglobulin Ab

A

Hashimoto thyroiditis

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Q

CTLA4, PTPN22 mutations

A

Hashimoto thyroiditis

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Q

Hurthle cell metaplasia

A

Hashimoto thyroiditis

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Q

Increased risk of Marginal Zone B-cell Lymphoma

A

Hashimoto thyroiditis

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Q

CTLA4, PTPN22, HLA-DR3 polymorphisms

A

Graves disease

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Q

Andes, Himalayas

A

Diffuse non-toxic goiter

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Q

RAS, PI3K, PTEN mutations

A

Follicular or Anaplastic thyroid carcinoma

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Q

BRAF mutation

A

Papillary thyroid carcinoma

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Q

Orphan Annie Eye nuclei

A

Papillary thyroid carcinoma

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Q

Ground glass appearance

A

Papillary thyroid carcinoma

Q

Pseudo-inclusions

A

Papillary thyroid carcinoma

Q

Neuroendocrine neoplasm in thyroid

A

Medullary thyroid carcinoma

Q

RET mutatin

A

Medullary thyroid carcinoma

Q

Stain + for calcitonin

A

Medullary thyroid carcinoma

Q

Amyloid deposits in stroma

A

Medullary thyroid carcinoma

Q

Carcinoembryonic Ag (CEA)

A

Sporadic medullary thyroid carcinoma

Q

HLA-DR3, DR4, DR8

A

DM1

Q

CTLA4, PTPN22, AIRE, Wasinsulin

A

DM1

Q

Serum glucose of 600-1200

A

Hyperosmolar Hyperosmotic Syndrome

Q

Serum glucose of 250-600

A

DKA

Q

Kimmelstiel-wilson disease

A

Nodular glomerulosclerosis in DM pts

Q

MEN1, PTEN, TSC2, ATRX syndrome, DAXX syndrome

A

Pancreatic neuroendocrine tumors

Q

Pancreatic cells with amyloid deposits

A

Insulinoma

Q

Stain + for PAS

A

Diffuse mesangial sclerosis

Q

Ki-67 and p16

A

HSIL

Q

PTEN, ARID1A mutations

A

Endometriosis

Q

Serous carcinoma mutation

A

TP53

Q

Mallignant Mixed Mullerian Tumor mutations

A

PTEN, TP53, PIK3CA

Q

Leiomyoma mutation

A

MED12

Q

Serous epithelial ovarian tumor mutation

A

BRCA1/2

Q

Mucinous epithelial ovarian tumor mutation

A

KRAS

Q

Endometrioid ovarian tumor mutation

A

PI3K/AKT

Q

Dysgerminoma mutations

A

OCT-3/4, NANOG

Q

Granulosa cell tumor mutation

A

FOXL2

Q

Stertoli-Leydig cell tumor mutation

A

DICER1

Q

Familial breast carcinoma genes

A

BRCA1/2, TP53, CHEK2

Q

Breast cancer gene associated with increased risk of ovarian carcinoma

A

BRCA1

Q

Breast cancer gene associated with increased risk of prostatic and pancreatic carcinoma

A

BRCA1/2

Q

HER2+ mutation

A

TP53

Q

ER+, HER2- mutations

A

BRCA2, PIK3CA

Q

ER-, HER2- mutation

A

BRCA1

Q

HOXB13 mutation

A

Phyllodes tumor