Pathogen Evasion Mechanisms (Cell-mediated & Humoral)

Question 1

Mycobacteria

Answer 1

Inhibits phagolysosome formation

Question 2

Herpes Simplex Virus

Answer 2

Inhibits antigen presentation via Fucking up TAP protein in MHC-I

Question 3

HIV, Influenza

Answer 3

Uses antigenic variation — changes antigens on it’s surface to avoid detection and destruction

Question 4

Epstein-Barr Virus

Answer 4

1) Inhibits antigen presenting via fucking up proteasome

2) Produces IL-10, reducing inflammation response

Question 5

Gonorrhea

Answer 5

Inhibits the complementary system

Question 6

Cytomegalovirus (CMV)

Answer 6

Inhibits antigen presentation via fucking up proteasome

Question 7

Pox virus

Answer 7

-Produces soluble cytokine receptors (competitively inhibits with proinflammatory cytokines)

Question 8

Streptoccocus

Answer 8

-Protective coating that prevents antigen binding and phagocytosis