Path of Immunity 2 Hypersensivity Reactions Flashcards
Hypersensitivity reactions
what are they?
the four mechanisms? what are each?
can you always tell there is a hypersensitivity reaction?
those you can?
those you cant?
Type of reaction you can recognize on sight?
examples?
Type 1 hypersensitivity reaction
pathway: what cell presents to what? this causes? 2
ending event? (specific receptor)
IL involved? each does what?
hypersensitivity type 1
what needs to happen for this reaction to occur?
this causes?
Type 1 hypersensitivity
Mast cell activation: 3 types of molecules released/activated?
what are the actual molecules?
the immediate response? 3
late phase? 3
What do you see clinically?
3
type 1 hypersensitivity reaction
immediate reaction what mediators? lead to?
late reaction what cells? lead to?
what point do you see more clinical manifestations?
what are each? what do you see in each?
what is this?
caused by?
symptoms? cause?
type 1 hypersensitivity role as doctor
3
how do you test for type 1?
mechanism?
type II hypersensitivity reaction
def?
mediators?
3 mechanisms type II
type II
opso/phago
mechanism? this leads to?
basic mechanism? so disease outcomes?
opso/phago type II
type II
complement and Fc receptor
basic mechanism?
leads to?
types?
type II
one complement/ Fc receptor disease?
acute? chronic?
mechanism?
will lead to?
type II complement/Fc other diseases?
type II antibody mediate cellular dysfunction
basic mechanism?
lead to? 2
type II anti-body mediated
3 diseases?
one interesting?
Type III hypersensitivity reaction
what is it?
type III
steps? 4
major organs that can be targets?
type III
2 types of disease?
s- acute due to? chronic from?
a- type of reaction? seen in?
serum sickness (reaction to proteins in serum)
type of staining?
help identigy what? stains what?
describe each picture
what makes them look like that?
which is what type of hypersensitivity reaction?
examples?
type shown in picture?
is a pic of kidney
special about this disease
type IV hypersensitivity reaction
mechanism?
pathways? 2
type IV
can you tell grossly?
ex?
hallmark of some type IV?
Type IV hypersensitivity reaction
the granuloma
what is it made up of? (type of cells)
origin from?
caused by?
type IV diseases?
type IV the mantoux test
what is it?
how long for reaction to be assessed?
reactions apparent based on presentation?
what is apparent?
reactiosn require knowing behind the scenes?
examples?
