Neoplasia 5 Lab Diagnosis Flashcards

1
Q

histologic and cytologic methods

lab diagnosis hard? what is?

sampling approaches of lab specimen?

frozen good?

A
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2
Q

Fine-needle aspiration

what is it? used on what type of lesions?

compared to needle biopsies?

A
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3
Q

cytologic smears

often used for? or what other situations?

limits of histo?

what overcomes limitations?

A
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4
Q

immunohistochemistry

what is it? helpful in what 3 situations?

A
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5
Q

flow cytometry

used for?

circulating tumor cells detected by?

A
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6
Q

Molecular and cytogenetic diagnostics

diagnosis of malignant neoplasms

how?

DNA microarrays for?

A
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7
Q

prognosis of malignant neoplasms

how so?

detection of minimal residual disease? monitors what? via?

diagnosis of hereditary predisposition to cancer

how so?

A
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8
Q

Guiding therapy with oncoprotein directed drugs

important why?

A
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9
Q

future of diagnosis

large scale anylsis. most common method?

DNA?

cost?

A
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10
Q

future

circos plots say what?

impact of cancer genome sequencing to date where?

helpful for what?

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11
Q
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12
Q

future

targeted therapies iportant?

best way to assess tumor: cell interactions

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13
Q

Tumor markers

biochem assays and tumor associated enzymes can be sued for?

PSA?

what problems with PSA?

A
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14
Q

tumor markers

other markers used? 4

CEA for?

AFP?

HCG?

CA-125

cell free DNAs evaluated as markers?

A
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