Path Buzzwords 6

Question 1

HSV management

Answer 1

Aciclovir, valaciclovir, famciclovir

Question 2

CMV management

Answer 2

Ganciclovir, foscarnet, cidofovir

Question 3

HBV management

Answer 3

Entacavir + pegylated interferon alpha 2a + tenofovir

Question 4

HCV management

Answer 4

Pegylated interferon alpha 2a/b + ribavirin

Question 5

Influenza neuraminidase inhibitor

Answer 5

Zanamivir, oseltamivir, amantadine

Question 6

High sodium and low potassium

Answer 6

Conn’s syndrome - also has high aldosterone and low renin

Question 7

Low sodium and high potassium

Answer 7

Addison’s disease - also has low glucose

Question 8

Chronic/asymptomatic hyponatraemia management

Answer 8

Hypovolaemic - 0.9% saline
Euvolaemic - TFT, short synacthen test, paired urine and serum osmolality
Hypervolaemic - fluid restriction + correct cause

Question 9

Hyperkalaemia management

Answer 9

10ml of 10% calcium gluconate
100ml of 20% dextrose
10 units of insulin

Question 10

Hypokalaemia management

Answer 10

3.0-3.5 - oral potassium

<3.0 - IV KCl

Question 11

Apple red birefringence on congo red stain

Answer 11

Amyloidosis

Question 12

Severity of CAP

Answer 12

Confusion
Urea >7
Respiratory rate >30
BP <90 systolic or <60 diastolic
>65 years
0-1 = outpatient
2+ = admit

Question 13

CAP management

Answer 13

Amoxicillin or macrolide (both for atypical)

Question 14

Pseudomonas pneumonia

Answer 14

Piptazobactam + vancomycin

Question 15

MTP inhibitor

Answer 15

Lomitapide

Question 16

Anti-PCSK9 monoclonal

Answer 16

Evolocumab

Question 17

Antisense apoB oligonucleotide

Answer 17

Mepomersen

Question 18

CJD treatment

Answer 18

Symptomatic - clonazepam

Delay conversion - quinacrine, pentosan, tetracycline

Question 19

Tumour necrosis factor alpha for RA, ankylosing spondilitis, CD, psoriasis

Answer 19

Infliximab

Question 20

CD20 monoclonal antibody for lymphoma, RA, SLE

Answer 20

Rituximab