Path Buzzwords 11

Question 1

Calcitonin

Answer 1

Medullary thyroid cancer

Question 2

Which vasculitis causes a disease in which a branch of the external carotid is affected?

Answer 2

Giant cell arteritis

Question 3

Causes of intravascular haemolysis

Answer 3

Malaria, G6PD deficiency, ABO mismatch, MAHA syndromes, paroxysmal nocturnal haemoglobinuria, drugs

Question 4

Causes of extravascular haemolysis

Answer 4

Autoimmune, alloimmune, hereditary spherocytosis

Question 5

Causes of MAHA

Answer 5

Haemolytic uraemic syndrome, disseminated intravascular coagulation, thrombocytic thrombocytopenic purpura

Question 6

Anti-alpha 4 integrin monoclonal

Answer 6

Natalizumab for MS

Question 7

HTLV-1

Answer 7

T cell lymphoma

Question 8

CTLA4-Ig fusion protein

Answer 8

Abatacept for resistant RA

Question 9

Guanine synthesis inhibitor

Answer 9

Mycophenalate mofetil for autoimmune disease and vaculitides

Question 10

Anti-IL-2 receptor antibody

Answer 10

Basiliximab for allograft rejection prophylaxis

Question 11

Antibody to p40 subunit of IL-12/23

Answer 11

Ustekinumab for psoriasis

Question 12

Alkylating agent for multi-system connective tissue disease and vasculitis

Answer 12

Cyclophosphamide

Question 13

Anti-CD11a antibody

Answer 13

Efalizumab for psoriasis

Question 14

Dermacentor tick

Answer 14

Rickettsia rickettsii -> Rocky Mountain spotted fever

Question 15

Thrombocytopenia + high ALT

Answer 15

Dengue fever

Question 16

Anti-IL-6 receptor

Answer 16

Tocilizumab for RA

Question 17

Anti-IL-17

Answer 17

Secukinumab

Question 18

Halo sign on CXR

Answer 18

Aspergillus

Question 19

Non-productive cough + CXR show ground glass appearance

Answer 19

PCP

Question 20

Genital warts

Answer 20

HPV 6 & 11

Question 21

Most common cause of PID

Answer 21

Chlamydia

Question 22

RANK ligand inhibitor

Answer 22

Denosumab for osteoporosis

Question 23

Anti-PD1

Answer 23

Pembrolizumab for malignant melanoma