Path 1.1 What is disease

Question 1

what is disease

Answer 1

disease results from the reaction from an injury but not the injruy itself

Question 2

how do our bodies factor into disease

Answer 2

out bodies reaction to the agent can kill the patient_.our body’s reaction to injury is the diease__reaction leads to macs that release tnf, vasodialation, hypovolemic shcok, death

Question 3

cell injury is both

Answer 3

reversible and irreversible

Question 4

reversible cell injury can lead to either

Answer 4

recovery or adaptation eg. Picking up a weight forming muscles

Question 5

irriversible cell injury can lead to either

Answer 5

apoptosis or necrosis

Question 6

what gets sick

Answer 6

cells not people

Question 7

A process that is ALWAYS pathological

Answer 7

necrosis

Question 8

a process that is natural and that the body uses in cell injury

Answer 8

apoptosis

Question 9

implications of injury

Answer 9

type, severity, duration, cell type (CT are tough), target of injury (protein, membrane..)

Question 10

critical needs of a cell

Answer 10

maintaining membrane integrity, generation of energy, synthesis of structural/functional components

Question 11

most poisonous toxin

Answer 11

diptheria toxin because it hinders ATP production by adp ribosylating EF1 and stopping protein synthesis

Question 12

hardy cells

Answer 12

macrophages_they don’t die so in HIV they are available to screw things up. Fibrobalsts and muscle cells are also good

Question 13

sensitive cells

Answer 13

neurons and cardiac myocytes bc they cannot divide__lots of disease involvging these wussies

Question 14

larges killer in western world

Answer 14

ischemia of cardiac myocytes and neurons (keeping them from getting oxygen)