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Pathology > 1.3 Mechanismss of Necrosis > Flashcards

1.3 Mechanismss of Necrosis Flashcards

0
Q

Inc Ca++ causes…(4)q

A 
(PAPE)...leads to membrane damage
Phospholipase
Protease
ATPase
Endonuclease
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1
Q

Mechanisms of Necrosis (6)

A 
(MOM CAP)
Dec ATP
Dec PH
O2 Radicals
Inc ITC Ca++
Inc membrane permeability
Irreversible mitochondrial damage
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2
Q

ATPase…

A

dec atp. no energy not life.

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3
Q

Phospholipase

A

chew up membranes

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4
Q

Protease

A

destroys cytoskeleton and other proteins

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5
Q

Endonuclease

A

Nuclear chromatin damage

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6
Q

free radicals

A

lipid peroxidation

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Pathology (26 decks)

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