Passmed Knowledge Flashcards

1
Q

What disease is associated with fevers, abdominal pain and gastro-intestinal symptoms, typically would cause swinging fevers as a result of the rupture of erythrocytic schizonts, as opposed to a constant one?

A

Malaria

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2
Q

What disease is associated with abdominal pain and fevers, and is typically associated with a ‘rose spot’ macular rash and a relative bradycardia?

A

Enteric fever

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3
Q

What disease is associated with the following presenting features?

Usually a large volume of fresh blood. Swallowed blood may cause melena. Often associated with haemodynamic compromise. May stop spontaneously but re-bleeds are common until appropriately managed.

A

Oesophageal varices

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4
Q

What disease is associated with the following presenting features:

Small volume of fresh blood, often streaking vomit. Malena rare. Often ceases spontaneously. Usually history of antecedent GORD type symptoms.

A

Oesophagitis

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5
Q

What disease is associated with the following presenting features?

Usually small volume of blood, except as a preterminal event with erosion of major vessels. Often associated symptoms of dysphagia and constitutional symptoms such as weight loss. May be recurrent until malignancy managed.

A

Cancer

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6
Q

What disease is associated with the following presenting features?

Typically brisk small to moderate volume of bright red blood following a bout of repeated vomiting. Malena rare. Usually ceases spontaneously.

A

Mallory Weiss tear

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7
Q

Which medication for T2DM have the beneficial side effect of weight loss?

A

SGLT-2 inhibitors

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8
Q

Which is the most common area to be affected by ischaemic colitis?

A

Splenic flexure

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9
Q

What investigation is used to confirm the diagnosis of diabetes insipidis?

A

Water deprivation test

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10
Q

What type of rash usually suggests graft vs host disease?

A

Painful maculopapular, after an allogenic transplant

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11
Q

What rash is usually non-itchy, and is a reaction to a recent infection or medication?

A

Erythema multiforme

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12
Q

What condition is a potentially fatal complication of longstanding under-treated hypothyroidism, and causes confusion and hypothermia?

A

Myxoedema coma

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13
Q

What is the most common organism found in central line infections?

A

Staph. epidermidis

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14
Q

When diagnosing a suspected DVT, if USS scan is -ve but D dimer is +ve, what is the next appropriate step in managing the patient?

A

Stop anticoagulation, repeat scan in 1wk

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15
Q

What angina medication may patients develop tolerance to, necessitating a change in regime?

A

Isosorbide mononitrate (nitrates)

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16
Q

What is the most appropriate first line anti-anginal treatment for stable angina in a patient with known heart failure, if there are no complications?

A

Bisoprolol

Should also be co-prescribed aspirin and simvastatin

17
Q

What angina medication is contraindicated if the patient already takes atenalol?

A

Verapamil - can cause heart block

18
Q

What is the most common type of prostate cancer?

A

Adenocarcinoma

19
Q

How is high INR (>8.0) and minor bleeding managed?

A

Stop warfarin, give IV vit K
Repeat if INR still high after 24hrs
Restart warfarin when INR <5.0

20
Q

A Bishop’s score greater than what indicates patient is likely to experience spontaneous labour and requires monitoring and reassurance?

A

8

21
Q

What antiviral medication is used to treat herpes zoster opthalmicus?

A

Oral aciclovir.

No requirement for steroids

22
Q

Combination of methotrexate and trimethoprim can cause what fatal reaction?

A

Bone marrow suppression and severe or fatal pancytopenia

23
Q

In an acute ischemic stroke, what is the time window for thrombolysis?

A

4.5hrs

24
Q

In an acute ischemic stroke, what is the time window for thromectomy?

A

6hrs

25
Q

What is the pharmacological treatment for stress incontinence?

A

Duloxetine

26
Q

What is the pharmacological treatment for urge incontinence?

A

antimuscarinics eg oxybutynin

27
Q

After their first VTE, what is the appropriate management for patients with antiphospholipid syndrome?

A

Lifelong warfarin

28
Q

What medications are used for opioid detoxification eg heroin?

A

Methadone and buprenorphine

29
Q

What is the emergency management for opioid overdose?

A

Naloxone (reverses the effects)

30
Q

What medications should be stopped in AKI due to the risk of worsening renal function?

A

ACE inhibitors eg enalapril, lisinopril, perindopril and ramipril.

31
Q

What is the appropriate first line management for acute pericarditis?

A

NSAIDs and colchicne