Passive Properties Flashcards

1
Q

What three positive properties properties are important to electrical signaling?

A
  1. Membrane resistance
  2. Axial resistance
  3. Membrane capacitance
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2
Q

How can you adjust passive properties to promote fast signaling?

A
  1. Increase membrane resistance.
  2. Lower axial resistance.
  3. Lower membrane capacitance
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3
Q

Are passive signals (local graded potentials), hyper or depolarizing?

A

Both

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4
Q

Are active signals (action potentials) hyper or depolarizing

A

Depolarizing

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5
Q

How do they record membrane potential?

A

Stimulating electrode and recording oscilloscope

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6
Q

Why does injecting a positive current result in depolarization?

A

When you inject a positive current you inject positive ions into the negative cell, making it less negative.

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7
Q

When you inject positive current, what is being measured?

A

The current that leaves the cell

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8
Q

Why does the membrane potential change more slowly than the current pulse?

A

The lipid bilayer holds onto some charge in the beginning.

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9
Q

What determines the change in membrane potential?

A

Membrane (input) resistance

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10
Q

How does neuronal size affect input resistance?

A

Larger equals more surface area. More surface area equals more channels. More channels lowers input resistance.

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11
Q

What is specific membrane resistance?

A

Property of membrane independent of size of the cell. Does depend on axon diameter though.

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12
Q

What is specific membrane capacitance?

A

Capacitance independent of size of the cell. Does depend on axon diameter though.

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13
Q

How does neuronal size affect input capacitance

A

Larger size equals more space for storage. More space equals more charge.

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14
Q

What is membrane current?

A

Total current

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15
Q

What is ionic current?

A

Current that goes through ion channels

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16
Q

What is capacitive current?

A

Current that goes onto lipid bilayer (capacitator)

17
Q

What is membrane time constant?

A

The time it takes to reach 63% of possible ionic current. Determines the time when the potential change reaches 63% of its value.

18
Q

How does size of cell body influence triggering an action potential?

A

If cell body is smaller, membrane (input) resistance is bigger. Which means that there can be a bigger change in membrane potential (better chance of clearing threshold).

19
Q

What is a better transmitter: axons or undersea cables?

A

undersea cables

20
Q

What is length constant?

A

The distance from the site of current injection, where potential reaches 37% of its original value

21
Q

What determines the value of initial peak potential?

A

Input resistance and current

22
Q

How can you speed up conduction velocity?

A

Increasing length constant while decreasing time constant?

23
Q

How do neurons speed up electrical signal propagation?

A
  1. Myelination (increases membrane resistance)
  2. Increase axon diameter