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RUSVM Virology Exam 2 > Parvoviridae > Flashcards

Parvoviridae Flashcards

1
Q

T/F: Parvoviridae is very stable,, making disinfection of contaminated premises very difficult

A

True

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2
Q

T/F: Infection of Parvoviridae leads to large intranuclear inclusion bodies

A

True

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3
Q

T/F: human parvovirus B19 is the same found in dogs and can be transmitted to humans from dogs or cats

A

False, B19 is different from that seen in dogs and cats and there is no evidence of transmission

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4
Q

What disease does feline parvovirus cause?

A

Feline panleukopenia (FPV)

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5
Q

T/F: FPV is not highly contagious or fatal

A

False, it is highly contagious and often fatal in cats and sever in kittens

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6
Q

How is FPV maintained in a population?

A

By environmental persistence

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7
Q

What are 3 ways FPV can be transmitted?

A
  1. Oro-nasally by infected animals, feces, secretions, or contaminated fomites
  2. In-utero
  3. Mechanical
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8
Q

What is the hallmark of he disease FPV?

A

Panleukopenia = destruction of WBC elements

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9
Q

In-utero infection of FPV of pregnant queens leads to what?

A
  1. Early fetal death
  2. Abortion
  3. Mummified births
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10
Q

In-utero infection of FPV closer to end of gestation leads to what?

A
  1. Kittens born with varying degrees of neural damage
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11
Q

T/F: cerebellar damage form FPV has been commonly reported

A

True

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12
Q

CS of FPV is most commonly seen in what age group of kittens?

A

3-5 months

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13
Q

MLV should not be administer to what 4 animals?

A
  1. Pregnant cats
  2. Immunosuppressed cats
  3. Sick cats
  4. Kittens less than 4 weeks old
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14
Q

What is one of the most common infectious disease in dogs?

A

Canine parvovirus 2 (CPV2)

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15
Q

What are the three antigenic variants of CPV2?

A

CPV2a, CPB2b, CPV2c

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16
Q

Which who antigenic variants of CPV2 are seen in N. America?

A

CPV2b and CPV2c

17
Q

Similar to FPV, CPV2 has what 3 main CS?

A
  1. Enteritis
  2. Myocarditis
  3. Panleukopenia
18
Q

Enteritis caused by CPV2 leads to what primary CS?

A

Hemorrhagic diarrhea

19
Q

T/F: serology is the best method to test CPV

A

False, not the best method bc most dogs have been vaccinated or previously exposed to CPV

20
Q

Due to potential damage by CPV to myocardial or cerebellar cells, which vaccine is preferred in pregnant dogs or colostrum-deprived puppies 6-8 weeks of age?

A

Inactivated vaccines

21
Q

T/F: oseltamivir can be used in the Tx of canine parvoviral enteritis

A

True

22
Q

T/F: Porcine parvovirus is an infectious cause of repro failure in swine

A

True

23
Q

What is the acronym for some of the manifestations of Porcine parvovirus?

A

SMEDI (stillbirth, mummification, embryonic death, infertility)

24
Q

What is the transmission route of porcine parvovirus (PPV)?

A

Oronasally in non-immune pregnant sows followed by transplacental transmission (venereal transmission is possible)

25
Q

T/F: death at different stages of pregnancy is typical of PPV infections

A

True

26
Q

What is a hallmark sign of PPV?

A

The increase of mummified fetuses after a normal gestation period

27
Q

T/F: abortions are common in PPV infections

A

False, abortions are uncommon

28
Q

T/F: PPV infections of embryo/fetus (<30days) leads to death and resorption of embryo/fetus, and the dam may return to estrus

A

True

29
Q

What happens during PPV infection of an early fetus (30-70days)?

A

Fetuses die and become mummified

30
Q

What happens during PPV infection of late fetus (>70days to term)?

A

Frequently develop lesions, but also mount an immune response and usually survive in-utero

31
Q

T/F: boars, sows, and gilts usually have inapparent CS or subclinical infections

A

True

32
Q

T/F: The major cause of SMEDI is porcine parvovirus

A

True

33
Q

T/F: serologic tests are of good value to Dx PPV

A

False; they are of limited value bc virus is widespread and vaccination may interfere

34
Q

T/F: PPV can cause persistent infections with periodical shedding of virus

A

True

35
Q

What is the best way to vaccinate for PPV?

A

Vaccinate all susceptible breeding stock twice, 2 weeks apart, several weeks before breeding

RUSVM Virology Exam 2 (10 decks)

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