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RUSVM Virology Exam 2 > Herpesviridae Part 1 > Flashcards

Herpesviridae Part 1 Flashcards

1
Q

What is the virus morphology of herpesviridae?

A

Enveloped, spherical to pleomorphic; with double stranded DNA

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2
Q

T/F: herpesviruses survive well outside host

A

False, do not survive well outside host

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3
Q

Who serve as a reservoir for transmission of herpesviruses?

A

Latently infected animals

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4
Q

What is a histological characteristic of herpesviruses?

A

Eosinophilic intranuclear inclusion bodies knows as type A cowdry bodies

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5
Q

What are the two important subtypes of bovine herpesvirus 1 (BHV1)

A
  1. BHV 1.1 (respiratory subtype)

2. BHV 1.2 (genital subtype)

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6
Q

Where are the sites of latency for BHV1?

A
  1. Trigeminal nerve: respiratory subtype

2. Sciatic nerve: genital subtype

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7
Q

What are the CS of the respiratory form of BHV1?

A

Red nose, necrotic rhinitis, dust pneumonia

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8
Q

T/F: IBR lesions are confined to the conjunctiva and no lesions are on the cornea, except diffuse edema

A

True

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9
Q

T/F: Abortions caused by BHV1 are often preceded by pustular vulvovaginitis

A

True

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10
Q

What are the 2 genital diseases caused by BHV1 in bovine?

A
  1. IPV (infectious pustular vaginitis)

2. Balanoposthitis

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11
Q

T/F: the paranteral vaccine for BHV1 is safe to used in pregnant cows

A

False, it causes abortion; the intranasal vaccine is safe to use in pregnant cows

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12
Q

What 2 infections does BHV2 cause?

A
  1. Bovine ulcerative mammillitis

2. Pseudo-lumpy skin disease

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13
Q

What are the two transmission routes of bovine ulcerative mammillitis caused by BHV2?

A
  1. Direct contact and vomited mediated

2. Mechanical transmission

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14
Q

T/F: in bovine ulcerative mammillitis caused by BHV2, there is a high incidence of mastitis

A

True

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15
Q

What infections does porcine herpesvirus 1/suid herpesvirus 1 cause?

A

Pseudorabies

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16
Q

Who are the primary reservoirs for pseudorabies caused by PHV1?

A
  1. Primarily recovered pigs

2. Rodents also

17
Q

T/F: Pseudorabies is shed in urine and feces

A

False; shed in saliva, nasal discharge and milk of infected pigs

18
Q

Who are the secondary hosts that pseudorabies can be transmitted to?

A
  1. Dogs and cats via ingestion of infected pig

2. Cattle via direct contact

19
Q

What is the primary site of viral replication for pseudorabies?

A

Upper respiratory tract

20
Q

What are the CNS lesions of pseudorabies?

A
  1. Ganglioneuritis
  2. Nonsuppurative meningoencephalitis
  3. Perivascular cuffing
21
Q

T/F: Pruritis (itching) is a dominant feature in primary hosts with pseudorabies

A

False, in secondary hosts

22
Q

T/F: piglets born to non-immune sows are most susceptible to pseudorabies and will show signs of CNS disease

A

True

23
Q

In cattle, a secondary host to pseudorabies, what CS are seen?

A

Intense pruritis, frenzy, death from resp. failure

24
Q

What are the CS of dogs, a secondary host to pseudorabies?

A

Frenzy and pruritis, self mutilation, drooling

25
Q

T/F: Cats, a secondary host of pseudorabies, pruritis may not be observed bc of rapid disease progression

A

True

26
Q

T/F: Vaccinations for pseudorabies can prevent infection

A

False, they reduce losses in enzootic areas and alleviate CS in pigs of certain ages

27
Q

What are two types of equine herpesviruses?

A
  1. Equine herpes virus 1 (EHV1)

2. Equine herpes virus 4 (EHV4)

28
Q

Which equine herpes virus is the most virulent?

A

EHV 1

29
Q

What two locations can a latent EHV 1 reside in?

A

CNS and lymph system

30
Q

What is the principle route of EHV1 infection?

A

Respiratory tract

31
Q

What is the main pathogenesis of EHV1?

A

Immunosuppression

32
Q

T/F: EHV1 can cause encephalomyelopathy (EHM) in horses of any age and breed

A

True

33
Q

The majority of abortions caused by EHV1 occurs during what stage of pregnancy

A

Last trimester

34
Q

What disease does EHV4 cause?

A

Equine viral rhinopneumonitis

35
Q

T/F: EHV 4 causes more severe tissue destruction than EHV1

A

False, causes less severe tissue destruction

36
Q

T/F: EHV4 rarely causes abortion when in infects pregnant mares

A

True

37
Q

T/F: EHV4 usuallly results in viremia

A

False, rarely results in viremia

38
Q

What kind of vaccines are available for EHV?

A

Live attenuated and inactivated commercial EHV 1 vaccine and combined product with EHV1 and EHV 4

RUSVM Virology Exam 2 (10 decks)

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