Circoviridae Flashcards

1
Q

What two infections does Circovirus cause?

A
  1. Porcine circovirus type-1 (non-path)

2. Porcine circovirus type-2 (PMWS)

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2
Q

What infection does gyrovirus cause?

A

Chicken infectious anemia

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3
Q

T/F: circovirus and gyrovirus both have circular, single stranded DNA, but circrovirus has ambisense DNA and gyrovirus has negative sense DNA

A

True

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4
Q

T/F: For circoviridae, virus replication occurs in non active cell

A

False, occurs in actively dividing cell

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5
Q

What cell structure does DNA replication occur for circoviridae?

A

Nucleus

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6
Q

Who is most commonly affects by PMWS caused by porcine circovirus 2 (PCV2)?

A

Pigs at 4-6 or 2-3 weeks post-weaning

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7
Q

What is the most common method of spread for PMWS caused by PCV2?

A

Fecal-oral transmission

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8
Q

T/F: Horizontal transmission occurs in swine with PMWS caused by PCV2

A

False, vertical transmission (transplacental infection)

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9
Q

How is PMWS caused by PCV2 distinctly characterized histologically?

A

Botryoid inclusion bodies in macrophages

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10
Q

Lymphoid depletion caused by PMWS causes a loss of what two types of cells?

A

B and T cells

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11
Q

T/F: subclinical infections are the most common CS of PMWS

A

True

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12
Q

T/F: PMWS can be severe with more pronounced lesions if there is a co-infection with other viruses

A

True

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13
Q

Is antigen detection for PMWS effective?

A

No, because most pigs are seropositive

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14
Q

What are 2 vaccinations for PMWS?

A
  1. Chimeric vaccine

2. Inactivated or baculoviruse-expressed vaccines

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15
Q

When are sows vaccinated for PMWS?

A

2 and 5 weeks antepartum

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16
Q

Porcine dermatitis and nephropathy syndrome (PDNS) is associated with what porcine virus?

A

PCV2

17
Q

Who is primary affected by chicken infectious anemia caused by PCV2?

A

Young chickens (2-4 weeks age)

18
Q

What are 3 transmission routes of chicken infectious anemia?

A
  1. Shed in feces and feather dander
  2. Horizontal via inhalation and oral route
  3. Vertically via egg
19
Q

T/F: The principal sites of replication for chicken infectious anemia are hemocytoblasts in bone marrow, precursor T cells in cortex of thymus, and dividing CD4 and CD8 cells in spleen

A

True

20
Q

What is the main Dx method for chicken infectious anemia?

A

Examination of blood: low PCV, watery blood, slow clotting