part5 Flashcards
Which one of the following organelles receives most of its protein contents directly from the endoplasmic reticulum:- a) peroxisomes, b) Golgi apparatus,
c) mitochondria, d) nucleus?
Golgi
What does FRAP stand for?
Fluorescent recovery after photobleaching
About how many different types of protein make up the nuclear pore in Saccharomyces cerevisiae:- a) 3, b) 30, c) 300, d) 3000?
30
Which is the only one of the following statements that could possible be true as a description of a fluorochrome:- a) it absorbs blue light and emits yellow;
b) it absorbs yellow light and emits blue;
c) it absorbs red light and emits yellow;
d) it absorbs yellow light and emits green?
a
Cultured CHO cells are commonly used in cell biology experiments. What does CHO stand for?
Chinese hamster ovaries
Which protein removes the inhibitory phosphates from CDKs?
Wee1
Name two ubiquitin ligases important in cell-cycle regulation.
SCF, APC
Name two of the inhibitors of CDK4/6.
P15, p16
Which one of the following is NOT a type of white blood cell:-
a) granulocyte, b) erythrocyte, c) lymphocyte, d) basophil?
b
What differentiated neural cell type in the central nervous system produces myelin?
oligodendrocyte
What one of the following is the function of transcription factors:- a) to block growth factor signalling, b) to activate but not repress gene transcription, c) to activate and/or repress gene transcription, d) to transcribe genes?
c
What biological process eliminates excess cells during development?
apoptosis
Which one of the following toxins does NOT target a cytoskeleton protein:-
a) phalloidin, b) latrunculin, c) ricin, d) colchicines?
c
What apparatus in the cell drives segregation of chromosomes at mitosis?
MT
The vesicles that carry cargo from the endoplasmic reticulum to the cis-Golgi are coated with which type of coat?
COPII
What does FRET stand for?
Flourescent resonance energy transfer
In which one of the following organelles does protein import occur mainly co-translationally:- a) mitochondria, b) nucleus, c) endoplasmic reticulum, d) peroxisomes?
ER
What is the term used to describe the highly concentrated solution of proteins and other macromolecules inside cells?
Cytoplasm
Name two ubiquitin ligases important in cell-cycle regulation.
APC, SCF
What gives the rough endoplasmic reticulum its characteristic “rough” appearance on electron micrographs?
Ribosomes
Which ATPase complex is thought to dissociate cis-SNARE complexes after membrane fusion?
NSF
Which one is of these is a phospholipid:- a) phosphatidylcholine, b) phosphatidylguanosine, c) diacylglycerol, d) phosphatidylinosine?
a
What is the major mitochondrial protein that initiates apoptotic cell death?
cytochrome c
Rank the following commonly used model organisms in terms of their genome size in MB (largest first):- a) Dictyostelium discoideum, b) Xenopus laevis, c) Escherichia coli, d) Arabidopsis thaliana.
D, b, a, c
