Part IX Flashcards

1
Q

What happens when one experiences oxygen toxicity?

A

seizures followed by coma within 30-60minutes

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2
Q

When the oxygen partial pressures are above 2 atmospheres, what happens?

A

free radical damage can form, which can damage cell membranes and cellular enzymes and the nervous tissue is highly susceptible, which results in brain dysfunction

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3
Q

How is oxygen toxicity preventable?

A

if one never exceeds the established max depth of a given breathing gas
and for divers, use “hypoxic blends” containing a lower O2% than ATM air

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4
Q

What is narcosis?

A

state of stupor, drowsiness or unconsciousness

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5
Q

How does one develop narcosis?

A

being submerged for over an hour

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6
Q

What happens at 120ft?

A

jovial, carefree

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7
Q

What happens at 150-200ft?

A

drowsiness

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8
Q

What happens from 200-250ft?

A

weakness

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9
Q

What happens above 250ft?

A

unable to function

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10
Q

What is the mechanism behind gas anesthetics?

A

dissolves in neuronal membranes altering ionic conductance

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11
Q

When is high PCO2 a problem?

A

almost never because depth doesn’t increase alveolar PCO2

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12
Q

When could PCO2 be increased?

A

in certain types of diving gear

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13
Q

What problems occur when CO2 toxicity does occur?

A

depression of respiratory centers, respiratory acidosis, lethargy, narcosis, anesthesia

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14
Q

What happens when a person breaths air under high pressure for an extended period of time?

A

the amount of N2 in the body fluids increases as higher N2 levels equilibrate with levels in tissues

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15
Q

Is nitrogen metabolized in the body?

A

no

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16
Q

When does the dissolved nitrogen come out of the tissues of the body?

A

when N2 pressure in the lungs decreases as the person ascend back to sea level

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17
Q

How much time is required to bring someone back up from under the sea? Why?

A

hours, the blood doesn’t flow rapidly enoguh and nitrogen doesn’t diffuse rapidly enough to cause instantaneous equilibration

18
Q

When is nitrogen dissolved in the blood a problem?

A

when someone has been under water for hours

19
Q

What is the Bends?

A

when nitrogen bubbles out of fluids after sudden decompression

20
Q

What can happen if nitrogen bubbles out of the blood?

A

can block blood vessels, large or small

21
Q

What are the symptoms of the bends?

A

pain in joints, muscles of arms and legs (85-90%), nervous system symptoms (5-10%), pulmonary capillaries blocked “the chokes” (2%)

22
Q

How do you prevent decompression sickness?

A

a diver who has been breathing air and has been on the sea bottom at a depth of 190 feet for an hour needs to stay underwater at various depths for about 3 hours

23
Q

Where does the lung rank as far as metabolism goes?

A

second to liver

24
Q

What is an advantage the lung has over the liver?

A

all blood passes through the lungs with every complete cycle

25
Q

What are some examples of metabolism that occurs in the lungs?

A

angiotensin I converted to angiotensin II

prostaglandins inactivated in one pass through pulmonary circulation

26
Q

How much air does the average adult breath in a day?

A

10,000 L of air/day

27
Q

What is in the air we breath?

A

inert dust, particulate matter (plants and animals), gases (fossil fuel combusion), infectious agents (viruses and bacteria

28
Q

What is a major source of contact with the environment?

A

respiratory membrane

29
Q

How many microns are between the air and blood?

A

.5 microns

30
Q

What do our defense mechanisms do?

A

protect tracheobronchial tree and alveoli from injury, prevent accumulation of secreions, repair

31
Q

What depresses defense mechanisms?

A

chronic alcohol use, cigarette smoke, air pollutants, occupational irritants

32
Q

Chronic alcohol use is associated with an increase incidence of what?

A

bacterial infections

33
Q

Cigarette smoke and air pollutants are associated with an increase incidence of what?

A

chronic bronchitis and emphysema

34
Q

Occupational irritants are associated with increase incidence of what?

A

hyperactive airways or intersitial pulmonary fibrosis

35
Q

What do nasal passages protect?

A

airwys and alveolar structures from inhaled foreign material

36
Q

What things help the nasal passage protect the respiratory system?

A

long hairs in nose filters our large particles, mucous coating nasal mucous membranes, nasal turbinates

37
Q

What are nasal turbinates?

A

highly vascularized structures that act as radiators to warm air

38
Q

What cranial nerve is associated with coughing?

A

CN X

39
Q

What is the process of coughing?

A

2.5L of air are rapidly inspired, epiglottis closes and vocal cords close tightly
muscles of expiration contract forcefully which causes pressure in lungs to rise to 100 mmHg
epiglottis and vocal cord open widely, which results in explosive outpouring of air to clear larger airways

40
Q

What is a cough ineffective at doing?

A

clearing smaller airways due to the total cross sectional area, it just can’t generate enough velocity