Parkinsons Flashcards
1
Q
where is there widespread degeneration when suffering from Parkinson’s?
A
substantia nigra - reduction in dopamine
2
Q
Lewy bodies
A
clumps of proteins in surrounding dopaminergic neuron’s of substantia nigra
3
Q
deep brain stimulation
A
subthalamic nucleus stimulated
4
Q
anterograde degeneration
A
distal segment - between the cut and the synaptic terminal
5
Q
retrograde degeneration
A
proximal segment - between cut and cell body
6
Q
transneuronal degeneration
A
degeneration spreads to nearby cells
7
Q
remyelination
A
implantation of stem cells
8
Q
foetal substantia nigra cell implant
A
successful in monkeys - tardive dyskinesia in humans
