Paramyxovirus Flashcards

1
Q

Paramyxoviruses are bad immunogens

A

False

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2
Q

Paramyxoviruses can survive just a few days in the environment

A

True

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3
Q

Paramyxoviruses cannot cause strong cytopathogenic effect in cell cultures

A

False

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4
Q

Paramyxoviruses are good immunogens

A

True

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5
Q

Parainfluenza viruses generally cause infection in the respiratory tract

A

True

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6
Q

Parainfluenza viruses are highly host specific

A

False

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7
Q

There are no vaccines on the market against canine parainfluenza 2 virus

A

False

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8
Q

Canine parainfluenza virus 2 frequently causes encephalitis in old dogs

A

False

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9
Q

Feline morbillivirus infection may be associated with tubulo-interstitial nephritis in cats

A

True

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10
Q

Parainfluenza virus 2 infection is frequent in the aetiology of kennel cough

A

False

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11
Q

Rinderpest virus can infect pigs

A

True

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12
Q

Rinderpest virus can infect cattle

A

True

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13
Q

The morbidity of rinderpest can reach 100%

A

True

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14
Q

Rinderpest virus replicated only in the lungs

A

False

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15
Q

Rinderpest virus is resistant; it can survive in the environment for several weeks

A

False

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16
Q

Rinderpest virus causes viraemia

A

True

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17
Q

Extended interstitial pneumonia is a frequent post mortem lesion of rinderpest

A

False

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18
Q

Vesicle formation on the mucous membranes is typical in the case of rinderpest

A

False

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19
Q

Diarrhoea with blood is a typical sign of rinderpest

A

True

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20
Q

Enteral clinical signs are not typical in Rinderpest

A

False

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21
Q

Attenuated viruses are widely used for the prevention of Rinderpest in Africa

A

False

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22
Q

The clinical signs of rinderpest and malignant catarrhal fever are similar

A

True

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23
Q

Erosions in the oral and nasal cavity are clinical signs of rinderpest

A

True

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24
Q

Rinderpest occurs in large number in Africa

A

False

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25
Q

Earth is free from Rinderpest

A

True

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26
Q

Wild mammals are asymptomatic carriers of Rinderpest

A

False

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27
Q

It is mandatory to vaccinate cattle against Rinderpest

A

False

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28
Q

Nowadays Rinderpest virus is used as heterologous vaccine against the PPR virus

A

False

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29
Q

Rinderpest virus survives for years in nature

A

False

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30
Q

Only cattle are susceptible to Rinderpest infections

A

False

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31
Q

Rinderpest is carried by animals for a long time

A

False

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32
Q

Rinderpest commonly occurs in Africa and in Latin America

A

False

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33
Q

Rinderpest virus is carried by animals for several years

A

False

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34
Q

Cattle are infected with rinderpest virus mainly per os

A

True

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35
Q

Cattle are affected with rinderpest mainly per os

A

True

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36
Q

Rinderpest virus can survive in the environment for several months

A

False

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37
Q

Peste des pest ruminants virus is resistant, it can survive in the environment for several months

A

False

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38
Q

Attenuated vaccines can be used for the prevention of peste des petit ruminants

A

True

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39
Q

Peste des petits ruminants is a widespread disease in Europe

A

False

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40
Q

Generally direct contact is needed to the transmission of peste des petits ruminants virus

A

True

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41
Q

Peste des petits ruminants virus replicates in the epithelium of the mucous membranes

A

True

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42
Q

Peste des petit ruminants is a frequently diagnosed disease in America

A

False

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43
Q

Necrosis of the oral epithelium is a typical sign of peste des petits ruminants

A

True

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44
Q

Peste de petits ruminants is a zoonotic disease

A

False

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45
Q

Nasal discharge is a typical clinical sign of peste des petit ruminants

A

True

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46
Q

Erosive lesions in the oral cavity are frequent signs of Peste des petits ruminants

A

True

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47
Q

The Peste des petits ruminants are endemic in North- and South America

A

False

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48
Q

Peste des petites ruminants virus can cause haemorrhagic pneumonia

A

True

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49
Q

Peste des petites ruminants virus can cause haemorrhagic or necrotic enteritis

A

True

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50
Q

Over 50% of the animals may die during a Peste des petits ruminants outbreak

A

True

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51
Q

The world is free of Peste des petites ruminants

A

False

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52
Q

Canine distemper virus can produce a generalised infection

A

True

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53
Q

The pathogenesis of distemper is influenced by the immune response of the host

A

True

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54
Q

Distemper can be prevented only with the attenuated but not inactivated vaccines

A

False

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55
Q

Distemper is zoonosis

A

False

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56
Q

Distemper virus is shed in respiratory discharge and urine

A

True

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57
Q

Canine distemper has six serotypes

A

False

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58
Q

Neurological signs are not typical signs of canine distemper

A

False

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59
Q

Clinical signs of the nervous system generally do not appear always in the case of canine
distemper

A

False

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60
Q

Canine distemper virus has one serotype with virulence variants

A

True

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61
Q

Salivation and chewing movements cannot be clinical signs of canine distemper

A

False

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62
Q

Distemper is a highly contagious disease of dogs and some other carnivores

A

True

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63
Q

Distemper can be prevented only with attenuated but not inactivated vaccines

A

False

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64
Q

Canine distemper virus causes immunosuppression

A

True

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65
Q

The dog is the only species which is susceptible to canine distemper virus

A

False

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66
Q

Three to six month old dogs are most susceptible to canine distemper virus

A

True

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67
Q

Enamel hypoplasia can be a sign of distemper

A

True

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68
Q

Hyperkeratosis of the nose and footpads are clinical signs of canine distemper

A

True

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69
Q

Ataxia and paralysis are the main clinical signs of distemper in cats

A

False

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70
Q

Distemper virus infects only dogs

A

False

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71
Q

Distemper can cause abortion

A

True

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72
Q

Dogs infected with Canine distemper virus usually become life-long carriers and shedders

A

False

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73
Q

Clinical manifestation of the Canine distemper is mainly seen in 3-4 months-old dogs

A

True

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74
Q

The outcome of Canine distemper virus infection is very much influenced by the immune
response of the dog in utero

A

True

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75
Q

Distemper virus infects only species belonging to Canidae

A

False

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76
Q

Distemper virus spreads mainly by droplet infection

A

True

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77
Q

Distemper virus can cause fetopathy

A

True

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78
Q

Distemper virus can infect species belonging to the Felidae

A

True

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79
Q

Distemper virus spreads mainly by arthropod vectors

A

False

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80
Q

Distemper is a notifiable disease

A

False

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81
Q

The dominant clinical sign of Canine distemper is diarrhoea

A

False

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82
Q

Canine distemper virus only infects Canidae

A

False

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83
Q

Distemper occurs in lions and dolphins

A

True

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84
Q

Distemper can cause encephalitis in dogs

A

True

85
Q

Surviving distemper does not result in protection

A

False

86
Q

Distemper can predispose dogs to secondary bacterial infections

A

True

87
Q

Vaccinations against distemper at half years of age

A

False

88
Q

Distemper causes de-myelinization

A

True

89
Q

Distemper through conjunctival smear can be diagnosed by immunofluorescence technique

A

True

90
Q

Canine distemper virus often causes cytoplasmic inclusion bodies in the urinary bladder
epithelial cells

A

True

91
Q

Hendra and Nipah viruses cause zoonotic disease

A

True

92
Q

Hendra virus can infect mainly swine and human

A

False

93
Q

Hendra virus can cause respiratory and neurological signs

A

True

94
Q

Hendra virus can cause respiratory and neurological signs

A

True

95
Q

Horse is susceptible to Hendra virus infection

A

True

96
Q

Hendra virus can cause enteritis in the small intestine

A

False

97
Q

Natural reservoir of Hendra virus is flying fox (bat)

A

True

98
Q

Hendra-viruses can cause encephalitis in horses and in humans

A

True

99
Q

Hendra virus is found only in Australia

A

True

100
Q

Diseases caused by Nipah virus occur worldwide

A

False

101
Q

Nipah virus can cause ataxia, spasms, and paralysis in pigs

A

True

102
Q

Natural reservoir of Nipah virus is fruit bats

A

True

103
Q

Wild birds may be reservoir hosts of the Nipah-viruses

A

False

104
Q

Nipah virus is transmitted mainly by arthropod vectors

A

False

105
Q

Bovine RS virus can cause severe pneumonia in 6 months to 2 years old calves

A

True

106
Q

Bovine respiratory syncytial virus replicates in the alveolar epithelium

A

True

107
Q

Worldwide occurrence is characteristic for Bovine respiratory syncytial virus infection

A

True

108
Q

Bovine respiratory syncytial virus causes viraemia

A

False

109
Q

Bovine respiratory syncytial virus can predispose to secondary bacterial infections

A

True

110
Q

Subcutaneous emphysema is a common clinical sign of the disease caused by bovine
respiratory syncytial virus

A

True

111
Q

Disease caused by bovine respiratory syncytial virus cannot be prevented with vaccination

A

False

112
Q

Bovine respiratory syncytial virus is spreading fast within a herd

A

True

113
Q

Bovine respiratory syncytial virus can cause life threatening disease in calves

A

True

114
Q

Bovine respiratory syncytial virus causes low morbidity and high mortality

A

False

115
Q

Bovine respiratory syntitial virus is caused by pneumovirus and we use inactivated vaccines for prevention

A

True

116
Q

Bovine parainfluenza virus causes central nervous clinical signs in calves

A

False

117
Q

Bovine parainfluenza-3 virus can result formation of hyalin membrane in the alveoli

A

True

118
Q

Disease caused by bovine parainfluenza-3 virus is very rare

A

False

119
Q

Bovine parainfluenza-3 virus can cause interstitial pneumonia in calves

A

True

120
Q

Bovine parainfluenza-3 virus infection is usually endemic in cattle farms

A

True

121
Q

Bovine parainffuenza-3 virus generally causes aerosol infection

A

True

122
Q

Fever, coughing, nasal discharge are common clinical signs of bovine PI-3 infection

A

True

123
Q

Disease caused by bovine parainfluenza 3 virus can be diagnosed using paired sera

A

True

124
Q

Bovine parainfluenza virus 3 is frequently endemic in cattle farms

A

True

125
Q

Parainfluenza 3 virus of cattle spreads mainly by arthropod vectors

A

False

126
Q

Symptoms of parainfluenza 3 virus infection of cattle are similar to RS virus infection

A

True

127
Q

Parainfluenza-3 virus of cattle can cause thromboembolic meningoencephalitis

A

False

128
Q

Parainfluenza-3 virus infection of calves is frequently followed by secondary bacterial
infection

A

True

129
Q

Parainfluenza-3 viruses causes disease primarily in young calves

A

True

130
Q

A common route of infection with parainfluenza-3 is through inhalation

A

True

131
Q

Parainfluenza-3 virus can predispose cattle to pneumonia caused by bacteria

A

True

132
Q

The main clinical sign of a parainfluenza-3 infection is diarrhoea

A

False

133
Q

Parainfluenza-3 virus aids in secondary bacterial contaminations

A

True

134
Q

Velogenic strains of Newcastle disease virus (NDV) cause an acute form of the disease

A

True

135
Q

Velogenic strains of Newcastle disease virus (NDV) cause an acute septicemia

A

False

136
Q

Live mesogenic strains of NDV are used for vaccinations in Europe

A

True

137
Q

Day-old chicken can be vaccinated with apathogenic strains to prevent ND

A

True

138
Q

Hen flocks are vaccinated with lentogenic/apathogenic strains to induce maternal immunity

A

True

139
Q

Mesogenic strains of NDV are used for vaccination in some countries

A

True

140
Q

Apathogenic trains of NDV are used for vaccination

A

False

141
Q

Velogenic-viscerotropic NDV strains can cause disease with high mortality

A

True

142
Q

ND is caused by virulent strains of the APMV-1 serogroup

A

True

143
Q

Members of every APMV serogroup can cause Newcastle disease

A

False

144
Q

It is possible to determine the virulence of AMPV-1 strains by sequencing

A

True

145
Q

A usual 1st symptom of neurotropic-vNDV infection is diarrhea

A

False

146
Q

An acute, nervous form of Newcastle disease can frequently be seen in ducks

A

False

147
Q

An acute, nervous form of Newcastle disease can frequently be seen in dogs

A

False

148
Q

Newcastle disease is caused by virulent strains of serogroup APMV-1

A

True

149
Q

An intracerebral pathogenicity index higher than 0.7 is a criterion of ND

A

True

150
Q

The sequence of Newcastle disease virus F0 splice is a significant factor in its virulence

A

True

151
Q

Newcastle Disease ND viruses cause dwarfism in embryonated chicken eggs

A

False

152
Q

There are no vaccines for the prevention of Newcastle disease

A

False

153
Q

Only faeces of the infected birds contains Newcastle disease virus

A

False

154
Q

Diarrhoea is a clinical sign of Newcastle disease

A

True

155
Q

Virulence of Newcastle disease virus can be characterised with the chicken embryo survival
index

A

True

156
Q

Newcastle disease is caused by avian paramyxovirus 1

A

True

157
Q

Newcastle disease virus can infect only chicken

A

False

158
Q

Worldwide distribution is common for Newcastle disease virus

A

True

159
Q

Inhalation is an important way of transmission of Newcastle disease virus

A

True

160
Q

Per os infection is an important way of transmission of Newcastle disease virus

A

True

161
Q

Eurasia is free from Newcastle disease

A

False

162
Q

Humans are resistant against Newcastle disease virus

A

False

163
Q

Lentogenic Newcastle disease virus cause severe fatal infection

A

False

164
Q

Lentogenic NDV may cause disease in young turkey

A

True

165
Q

Germinative infection is an important way of transmission of Newcastle disease virus

A

False

166
Q

Lentogenic Newcastle disease virus cause severe fatal infection

A

False

167
Q

Lentogenic Newcastle disease virus can cause high morbidity and mortality in poultry flocks

A

False

168
Q

Lentogenic Newcastle disease virus is more virulent than velogenic

A

False

169
Q

Newcastle disease virus causes viraemia

A

True

170
Q

Newcastle disease virus damages blood vessels

A

True

171
Q

The clinical signs of Newcastle disease and avian influenza are similar

A

True

172
Q

Virulence of Newcastle disease virus can be characterised with the intracerebral
pathogenicity index

A

True

173
Q

There are different virulence variants of Newcastle disease virus

A

True

174
Q

Only inactivated vaccines may be used for the prevention of Newcastle disease

A

False

175
Q

Velogenic Newcastle disease virus is more virulent than mesogenic

A

True

176
Q

Tremor, spasms and torcicollis are clinical signs of Newcastle disease

A

True

177
Q

Newcastle disease, splice site significant

A

True?

178
Q

Index higher than 0,7 is a criterion of Newcastle disease

A

True

179
Q

Vaccination against Newcastle disease is used all over world

A

True

180
Q

The vaccine for NDV is a lentogenic strain

A

True

181
Q

Lentogenic stain is used in vaccines for new castles disease

A

True

182
Q

Newcastle disease virus velogen viscerotop and neurotrop causes neurological signs

A

True

183
Q

Wild birds may be reservoir hosts of the Newcastle disease virus

A

True

184
Q

The virulence of Newcastle disease strains can be determined by sequence analysis of
certain genes

A

?

185
Q

Newcastle disease virus cannot survive long in the environment

A

False

186
Q

Newcastle disease virus is typically vectored by ticks

A

False

187
Q

Velogenic strains of Newcastle disease virus always cause encephalitis

A

True

188
Q

Lentogenic strains of Newcastle disease virus can be used for vaccine production

A

True

189
Q

Lentogenic strains of Newcastle disease virus can cause high morbidity and mortality

A

False

190
Q

Velogenic viscerotrop strains of Newcastle disease virus can be used for vaccine production

A

False

191
Q

Avian paramyxoviruses (APMV) belong into 9 serogroups

A

True

192
Q

Lentogenic strains of Newcastle disease virus do not cause clinical signs

A

False

193
Q

Wild boars may transmit Newcastle disease virus

A

False

194
Q

Any member of the avian paramyxovirus serogroups may cause Newcastle disease

A

False

195
Q

Avian paramyxovirus-1 usually causes central nervous disease in pigeons

A

True

196
Q

Newcastle disease virus can be taken up by inhalation and per os

A

True

197
Q

CNS clinical signs are frequently seen in chicken in the case of Newcastle disease

A

True

198
Q

Newcastle disease could easily be differentiated from avian influenza

A

False

199
Q

Using vaccines of velogenic strains of Newcastle disease virus good protection can be
reached

A

False

200
Q

Drop of egg production is a clinical sign of avian metapneumovirus infection

A

True

201
Q

Avian metapneumovirus infection occurs only in America

A

False

202
Q

Avian metapneumovirus infection spreads very fast within the flock

A

True

203
Q

Disease caused by avian metapneumovirus is more severe in turkeys than hens

A

True

204
Q

In avian metapneumovirus infection the egg production drops/decreases

A

True

205
Q

Swollen head syndrome (SHS) caused by avian metapneumonia virus

A

True

206
Q

Wild birds may be reservoir hosts of avian metapneumoviruses

A

True

207
Q

Avian metapneumoviruses can cause respiratory signs and egg production problems

A

True

208
Q

Turkey rhinotracheitis virus causes disease in turkeys and chickens

A

True

209
Q

Turkey rhinotracheitis is most frequent at 4-9 weeks of age

A

True