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EPI 1 > Orthomyxovirus/Influenza > Flashcards

Orthomyxovirus/Influenza Flashcards

1
Q

Influenzaviruses have segmented genome

A

T

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2
Q

HPAI and LPAI strains differ in the number of basal amino acids in the HA protein

A

T

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3
Q

HA protein of influenza viruses is responsible for the attachment to the cell

A

T

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4
Q

The M2 protein of influenza viruses serves as an ion channel important in the decapsidation

A

T

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5
Q

Antigenic drift means serials of point mutations in the HA and NA genes

A

T

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6
Q

The NA protein in the influenza virus is responsible for the release from the infected cells

A

T

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7
Q

Enzymatic cleavage of the HA protein is needed for the influenza virus penetration into the cell

A

T

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8
Q

Genetic reassortment of human and animal influenza viruses result in the occurrence of new
human influenza strains

A

T

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9
Q

Bats have an important role in the epidemiology of influenza

A

F

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10
Q

Antigenic shift is behind the influenza pandemics

A

T

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11
Q

Influenza viruses are classified into genera by their HA and NA proteins

A

F

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12
Q

Influenza causes persistent infection in donkey

A

F

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13
Q

The serotype of influenza viruses is determined by their HA and NA proteins

A

T

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14
Q

The influenza viruses cause respiratory signs in sea mammals

A

T

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15
Q

The host range of influenza virus is determined by the NA protein

A

F?

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16
Q

The bird to human host switch of influenza virus is mediated by swine

A

T

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17
Q

The main host of influenza is the swine

A

F

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18
Q

In humans inactivated vaccines are used for the immunisation against influenza

A

T

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19
Q

Antigenic drift is behind the seasonal influenza epidemics

A

T

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20
Q

Antigenic shift means the reassortment of the influenzavirus genome segments

A

T

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21
Q

Influenzaviruses are sensitive to drying out

A

T

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22
Q

For the in vitro propagation of influenza viruses embryonated eggs is used

A

T

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23
Q

The high virulence of some influenza A viruses is the result of mutations in the HA gene

A

T

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24
Q

Influenza viruses are classified into genera by their HA and NA proteins

A

F

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25
Q

Dogs are susceptible to horse origin influenza strains

A

T

26
Q

The HPAI strains can cause CNS signs

A

T

27
Q

HPAI causes blood vessel damages and generalised infections

A

T

28
Q

The HPAI strains are usually developed from the H5 and H7 influenza viruses

A

T

29
Q

The LPAI causes immunosuppression

A

T

30
Q

Cat is susceptible to human seasonal influenza

A

F

31
Q

HPAI strains are mutations of LPAI strains

A

T

32
Q

HPAI strains belong into a certain haemagglutinin types

A

F

33
Q

Influenzas Causes enteric symptoms in human.

A

T

34
Q

Anti-neuraminidase drugs inhibit the decapsidation of influenza viruses

A

F

35
Q

Swine recovered from influenza should not be kept for breeding

A

T

36
Q

Influenza causes high morbidity but low mortality in swine

A

T

37
Q

The HPAI causes skin haemorrhages in swine

A

F

38
Q

Swine influenza outbreaks occur usually during summer

A

F

39
Q

The mortality of swine influenza is high

A

F

40
Q

Swine influenza causes high morbidity rate

A

T

41
Q

To prevent complications of swine influenza penicillin injections are given to sick pigs

A

T

42
Q

Swine influenza is easily transmitted to people

A

F?

43
Q

To prevent complications of swine influenza, antibiotics used

A

T

44
Q

In swine all influenza variants can be detected

A

F

45
Q

In a horse influenza outbreak all infected horses must be killed

A

F

46
Q

The generalized symptoms of horse influenza are result of the interferon response

A

T

47
Q

Racehorses should be vaccinated before the influenza season

A

F

48
Q

Breeding mares should be vaccinated before the influenza season

A

F

49
Q

Influenza causes persistent infection in horses

A

F

50
Q

The eggs produced in LPAI infected flock can be hatched

A

T

51
Q

The HPAI infection can be unambiguously differentiated from Newcastle disease by the
clinical signs

A

F

52
Q

The HPAI strains can cause clinical signs in waterfowl

A

T

53
Q

In poultry farms LPAI may be endemic without clinical signs

A

T

54
Q

Waterfowl can carry the influenza viruses for long time

A

T

55
Q

Influenza viruses are shed by birds exclusively in the nasal discharge

A

F

56
Q

Avian influenza is zoonotic

A

T

57
Q

The virulence of avian influenza is determined by the i.v. pathogeny index and mortality

A

T

58
Q

Avian influenza can switch directly to human and cause epidemics with high case numbers as result of human to human transmission

A

F

59
Q

In birds all influenza variants can be detected

A

T

60
Q

Avian influenza of high economic impact is caused by HPAI strains

A

T

61
Q

Avian influenza virus is primarily spread through bronchial discharge and aerogenic route

A

F

62
Q

Avian influenza spread by bronchial discharge

A

T??

EPI 1 (56 decks)

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