paper 1: All Cells Arise from Other Cells Flashcards

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1
Q

what is a chromosome

A

one DNA molecule folded into a condensed form, wrapped around histone proteins in eukaryotes

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2
Q

after DNa replication what is a chromosome made of

A

2 genetically identical sister chromatids

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3
Q

show a chromosome before and after DNA replication

A
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4
Q

how are chromosome homologous pairs

A

one chromosome is inherited from the mother and one chromosome is inherited from a father

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5
Q

what is the definition of a homologous chromosome

A

the same genes but potentially different alleles

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6
Q

define a gene

A

a section of DNA that codes for a polypeptide or functional RNA

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7
Q

define an allele

A

different forms of the same gene that code for a specific trait

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8
Q

what is a chromosome number

A

the number of chromsomes possessed by an organism (n)

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9
Q

define a diploid cell

A

diploid cells have a homologous pairs of chromosomes

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10
Q

what is a haploid cell

A

haploid cells have one copy of each homologous chromosome

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11
Q

what are the main stages of the cell cycle

A
interphase
prophase 
metaphase 
anaphase
telophase
cytokinesis
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12
Q

define mitosis

A

cell division that produces 2 genetically identical daughter cells from a parent cell

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13
Q

why do cells need to carry out mitosis

A

growth and repair tissues & replace cells

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14
Q

what happens during interphase

A
  • new proteins are synthesised
  • DNA replicates
  • new organelles are made
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15
Q

when are chromosome visible

A

in the stages of mitosis

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16
Q

what happens during prophase

A
  • chromosomes condense and become visible
  • nuclear membrane breaks down centrioles move to opposite poles of the cell
  • spindle fibres form
17
Q

what happens during metaphase

A
  • spindle fibres attach to centromere
  • chromosomes are lined up at the equator of the cell
18
Q

what happens during anaphase

A
  • spindle fibres contract splitting the centromere
  • v-shaped sister chromatids are separated and pulled apart to opposite poles of the cell
19
Q

what happens during telophase

A
  • spindle fibres break down
  • a new nuclear membrane forms around each group of chromosomes
  • chromosomes uncondense
20
Q

what happens during cytokinesis

A

the cytoplasm divides into 2 to create 2 separate daughter cells

21
Q

how does cancer forms

A
  • if a mutation occurs in one of the control genes, then cell division continues
  • uncontrolled cell division can lead to the formation of tumours and cancers
  • mutation occurs at random
  • mutagenic agents increase the chances if mutation
22
Q

what are some examples of mutagenic agents

A
  • UV radiation, ionising radiation, carcinogens (cigarettes, asbestos)
23
Q

what are the 2 types of tumour

A

benign and melignant

24
Q

what are benign tumours

A

slow growing tumours that don’t spread to the rest of the body

25
Q

what are melignant tumours

A

fast growing tumours that cells break off of and spread to other parts of the body

26
Q

what is the difference between a tumour and a cancer

A

a tumour is a mass of cells dividing uncontrollably, if those cells break off and spread it becomes a cancer

27
Q

how do cancer treatments control the rate of cell division

A
  • prevents the synthesis of enzymes needed for cell replication
  • damage DNA
  • prevent the formation of spindle fibres
28
Q

what is a negative of cancer treatments

A

the treatments cannot distinguish between healthy and cancerous cells so they destroy normal body cells that are dividing

29
Q

how do prokaryotic cells replicate

A

a process called binary fission

  • the circular DNA and the plasmids replicate
  • the copies of circular DNA move to separate poles of the cell
  • the cytoplasm divides to produce 2 daughter cells
  • each cell contains a single copy of the circular DNA but a variable number of plasmids
30
Q

how do viruses replicate

A
  • they use a specific host cell to replicate
  • the virus attachment protein binds to a specific complimentary receptor protein on a specific host cell
  • the viral DNA/RNA is injected into the host cell
  • the host cell uses the viral genetic material and its own ribosomes and enzymes to synthesise viral proteins
  • the viral particles are formed and release from the host cell