pancreatic cancer Flashcards

1
Q

most common histology

A

adenocarcinoma

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2
Q

most common location

A

head of pancreas

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3
Q

how can pancreatic cancer cause obstructive jaundice

A

if tumour in head grows big enough it will compress bile ducts

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4
Q

presentation

A

painless obstructive jaundice

  • yellow skin + sclera
  • pale stools
  • dark urine
  • itching

also

  • abdo or back pain
  • weight loss
  • epigastric mass
  • change bowel habit
  • N/V
  • new onset diabetes or worsening of T2DM
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5
Q

when to refer for suspected pancreactic cancer

A

over 40 w jaundice - 2wk wait referral

over 60 with weihgt loss + additional symtom - direct access CT referral

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6
Q

refer for direct access CT abdo to assess for pancreatic cancer if patient has weight loss plus any of….

A
diarrhoea
back pain 
abdo pain 
nausea
vomiting
constipation 
new onset diabetes
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7
Q

courvoisier’s law

A

palpable gallbladder with jaundice is unlikley to be gallstones

–> cholangiocaricnoma or pancreatic cancer

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8
Q

Trousseau’s sign of malignancy

A

migratory thrombophlembitis - blood vessels inflamed with assoc blood clot

pancreatic adenocarcinoma

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9
Q

Ix

A

CT
MRPC
ERCP
biopsy

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10
Q

Mx - surgical opitons

A

total pancreatectomy
distal pancreatectomy
whipple
modified whipple

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11
Q

Mx - when is surgery considered

A

small tumour isolated to head

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12
Q

Mx - palliative options

A

stents
surgery
palliative chemo, radio

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13
Q

what is a Whipple

A

pancreaticduodenectomy

removal of

  • head panceras
  • stomach pylorus
  • duodenum
  • gallbladder
  • bile duct
  • relevant lymph nodes
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