cholangiocarcinoma Flashcards
1
Q
cholangiocarcinoma
A
cancer originating in bile ducts
most often adenocarcinoma
2
Q
most common site
A
perihilar region
where R and L hepatic ducts have just become common hepatic duct
3
Q
key risk factors
A
primary sclerosing cholangitis ( worth remembering assoc w UC) liver flukes (parasitic infection)
4
Q
presentation
A
obstructive jaundice pale stools, dark urine, itching
weight loss
RUQ pain
palpable gallbladder
5
Q
Couroisier’s law
A
palpable gallbladder along with jaundice unlikely to be gallstones
cause usually cholangiocarcinoma or pancreatic cancer (P ca more common)
6
Q
Ix
A
staging CT
CA19-9
MRCP
ERCP + biopsy
7
Q
Mx
A
curative surgery if early disease, can be used with chemo/radio
most often palliation
8
Q
Mx - palliative treatment
A
stent
chemo
radio
symptom control
