colorectal cancer Flashcards

1
Q

Duke A

A

confined to mucosa

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2
Q

Duke B

A

through muscularis propria

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3
Q

Dukes C

A

lymph node

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4
Q

Duke D

A

distant metastases

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5
Q

T1

A

into submucosa

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6
Q

T2

A

into muscularis propri

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7
Q

T3

A

though muscularis propria into subserosa

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8
Q

screening

A

2yrly FIT test
age 60-74
(50-74 in scotland)

if positive then colonoscopy

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9
Q

urgent 2 wk wait - ≥40 with

A

unexplained weight loss and abdo pain

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10
Q

urgent 2 wk wait - ≥50 with

A

unexplained rectal bleeding

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11
Q

urgent 2 wk wait - ≥60 with

A

iron deficiency anaemia
or
change in bowel habit

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12
Q

urgent 2 wk wait - <50 with

A

rectal bleeding plus any of

  • abdo pain
  • change bowel habit
  • weight loss
  • iron deficient anaemia
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13
Q

FAP

A

autosomal dominant

develop hundreds of adenomatous polyps in teens

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14
Q

HNPCC

A

autosomal dominant

mutation of mismatch repair genes

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