Pancreatic CA Flashcards
What is Pancreatic CA a major cause of?
major cause of all CA deaths from CA
What is the mortality rate of pancreatic CA in first year?
~90%
Which populations has high rate of Pancreatic CA? (3)
Higher is….
Men
Smokers
Black population
What does it mean: several cig smokes are organ specific carcinogens?
When smoke is inhaled and absorbed into circulation it target sites and trigger mutations and bring about malignancies
Etiology (6)
- smoking
- alcohol
- ageing
- DM
- chronic pancreatitis
- poor diet
Etiology:
Which is a major risk? (1)
Which makes a direct contact to liver? (1)
smoking
alcohol
Which age group is most affected? Is it rare in young or old pop?
> 50 years old
rare in younger populations
Etiology: Which is considered a risk factor? Which is linked but mechanism is unclear?
- DM
2. chronic pancreatitis and poor diet
90% of pancreatic CA is mostly ___________. What type of tissue is it in?
- adenocarcinomas
- duct epithelium (epithelial tissues) –>proliferate easily
also endocrine tissues
What are the classic mnfsts? (3)
- jaundice: d/t association of pancreas and liver
- abdominal pain: impacts nerves, blood vessel, and tissue in the area
- weight loss
Are mnfst specific or non-specific?
non-specific; not directly obvious to the malignancy of the pancreas
T or F: The classic mnfsts are related to the decrease fxn of pancreas
F: it is related to the mass of tumor
Diagnosis of Pancreatic CA (2)
- US
- CT
Imaging in the abdominal cavity to detect issues in pancreas, liver, and colon but expensive and long waitlist
Is metastasis early or late? what does that mean?
early mets = poor prognosis
Is there screening tests for early detection?
NOOOOOOOOOOOOOOOO
