Pancreas and liver

Question 1

What are the three things that chyme are?

Answer 1

Hypertonic
Low pH
Partially digested

Question 2

What does the hypertonic nature of chyme allow?

Answer 2

water from the ECF and circulation to enter chyme in the duodenum (stomach not permeable to water)
Must be controlled to not overwhelm

Question 3

What does the low pH of chyme allow?

Answer 3

Secretions from the pancreas and liver e.g. enzymes, bicarbonate, bile

Question 4

What is secreted from the duodenum?

Answer 4

CKK and secretin

Question 5

What does secretin do?

Answer 5

Secretin acts on pancreas to stimulate bicarbonate components of pancreas secretions

Question 6

What does CKK do?

Answer 6

CKK acts on pancreas to stimulate enzyme components of pancreas secretion

also acts on gallbladder by contracting but also relaxes sphincter of oddi and

Question 7

What stimulates the pancreas to secrete?

Answer 7

CKK
Secretin
Sympathetic inhibits and parasympathetic stimulates

Question 8

What does CCK stimulate exactly? (and vagus nerve)

Answer 8

Acini cells

Question 9

What do acini cells do?

Answer 9

Produce enzymes
Amylase and lipase
And inactive proteases

Question 10

What happens to inactive proteases?

Answer 10

Concentrated and stored in zymogen granules
These contains zymogen which is trypsinogen which can be converted into trypsisn in interstitual lumen
When active- trypsin, chymotrpsin, elastase and carboxypeptidase