Pain physiology Flashcards
What is nociception?
The neural mechanism by which an individual detects the presence of a potentially tissue harming stimulus
What are the 4 processes of nociception?
- Transduction
- Transmission
- Modulation
- Perception
What is the benefit of pain?
Acute survival, protective measure
What is the disadvantage of pain?
Catabolic stress response - no longer needed
Chronic pain is pathological
What systems are affected by the acute catabolic stress response of pain?
- CNS
- CVS
- Resp
- GIT
- GUS
- Muscular
- Metabolic
What is the affect of pain on the CNS?
- anxiety
- depression
- sleep impairment
What is the affect of pain on the CVS?
- Increased blood pressure
- increased heart rate
- Increased ischaemic heart disease
What is the response of pain on the respiratory system?
- inhibits the cough reflex
- Hyperventilation
What is the effect of pain on the GIT?
- nausea
- vomiting
What is the effect of pain on GUS?
- urinary retention
- uterine inhibition
What is the effect of pain on the muscles?
- restless (O2)
- immobility
What are the metabolic effects of pain?
Increased catabolic - cortisone, glucagon, growth hormone, catecholamines
Decreased anabolic - insulin, testosterone
Decreased plasminogen - increasing coagulation and DVT
