Pain and Touch Flashcards

1
Q

A stimulus to the receptor produces a _____.

A

graded potential

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2
Q

If the graded potential generated by a stimulus is large enough, the receptor generates an _____.

A

action potential

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3
Q

Patterns of action potentials are _____ in a sensory system.

A

coded

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4
Q

A single neuron can convey stimulus intensity by changing the _____ of its action potentials.

A

frequency

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5
Q

Multiple neurons can act in _____ to strengthen the stimulus.

A

unison

as the stimulus strengthens, more neurons are recruited

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6
Q

Different neurons respond to different ranges of _____.

A

intensity

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7
Q

Range fractionation

A

different cells have different thresholds for firing, over a range of stimulus intensities

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8
Q

The _____ system detects touch and pain.

A

somatosensory

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9
Q

The four touch receptor classes are _____, _____, _____, and _____.

A

pain, touch, vibration, stretch

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10
Q

Free nerve endings reside in the _____ and respond to _____ and _____.

A

epidermis, pain, temperature

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11
Q

Merkel’s discs reside in the _____ and respond to _____.

A

epidermis, touch

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12
Q

Meissner’s corpuscles reside in the _____ and respond to _____.

A

dermis, touch

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13
Q

Pancinian corpuscles reside in the _____ and respond to _____.

A

dermis, vibration

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14
Q

Ruffini’s endings reside in the _____ and respond to _____.

A

dermis, stretch

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15
Q

Temperature receptors use the _____ pathway.

A

pain

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16
Q

Small _____ C fibers respond to _____ and _____.

A

unmyelinated, dull pain, low temperatures

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17
Q

_____ A-delta fibers respond to _____ and _____.

A

Myelinated, sharp pain, high temperatures

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18
Q

Capsaicin activates _____ via TRVP1 and is a _____.

A

C fibers, neurotoxin

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19
Q

Pancinian corpuscles run through _____.

A

dorsal root ganglia

20
Q

A dorsal root ganglion is comprised of _____.

A

unipolar cells

21
Q

Tonic receptors _____ action potential frequency.

A

gradually decrease

22
Q

Phasic receptors _____ action potential frequency.

A

quickly decrease

23
Q

Receptive fields contain the property of _____.

A

a single neuron

24
Q

Receptive fields differ in _____ and _____.

A

size, shape

25
Most sensory pathways pass through the _____ and end in the _____.
thalamus, cerebral cortex
26
the somatosensory cortex _____ after amputation of a hand.
reorganizes
27
substance P is a _____ essential to responding to _____.
neurotransmitter, pain
28
Congenital insensitivity to pain is caused by inherited _____ in pain fibers in _____.
mutated sodium channels, dorsal root ganglia
29
Man on fire syndrome is cause by congenital _____ to pain.
hypersenstivity
30
The spinothalamic system transmits _____ and _____.
pain, temperature
31
Periaqueductal gray in the _____ is involved in _____.
midbrain, pain perception
32
C fiber gates can be closed by increased activity in _____.
A fibers
33
_____ delivers electrical pulses to the skin.
Transcutaneous electrical nerve stimulation (TENS)
34
Neurogenic pain
pain resulting from damage to nerves
35
Psychogenic pain
pain not due to disease, injury or any visible damage
36
Reflex Sympathetic Dystrophy results in _____, _____ (stage 1), _____, _____, and _____ (stage 2)
``` increased sensitivity of skin to touch (stage 1) localized swelling Swelling tends to spread (stage 2) Hair and nails become brittle Muscle wasting begins ```
37
Neurogenic pain is due to _____ of pain by neurons
inappropriate signaling
38
Postsynaptic spinal cord neurons take up _____, released during _____, and remodel their _____.
substance P, pain, dendrites
39
_____ of sympathetic input leads to dorsal horn neurons becoming _____: Increased spontaneous activity and response to all touch.
Overactivity, hyperexcitable
40
Patients with chronic pain have overactive _____ at rest.
somatosensory cortex
41
Sensory Integration Disorder results in stimulus _____ and _____.
avoiders, seekers
42
Synesthesia
a stimulus in one modality creates a sensation in another | this food tastes blue
43
Synesthesia results from _____, _____, or _____.
LSD posterior temporal lobe seizure result of blindness or deafness
44
Pain is ultimately processed in the _____.
singulate gyrus
45
The somatosensory cortex composed of half _____ and half _____ receptors.
Tonic, Phasic
46
_____ is the ability to sense orientation, location, and position of body parts.
Proprioception