Pain and Analgesics

Question 1

Pain, inflammation and fever are important physiological responses
to injury and infection. What are 4 Signs and Symptoms?

Answer 1

1. Redness
2. Heat
3. Swelling
4. Pain

Question 2

What are Nociceptors?

Answer 2

Sensory Neurons; respond to tissue damage or potentially tissue damaging stimuli

Question 3

What is the Classification, Indication for Use, 2 Common Side Effects and Nursing Actions for Simvastatin?

Answer 3

Classification: Hypolipidaemic
Indication for Use: High Cholesterol
2 Common Side Effects:
1. Constipation
2. Stomach Pain
Nursing Actions:
Monitor liver function and cholesterol levels

Question 4

What does the COX Enzyme produce?

Answer 4

Prostaglandins

Question 5

What do COX 1 Enzymes do?

Answer 5

Involved in platelet aggregation

Question 6

What are COX 2 Enzymes responsible for?

Answer 6

Mediators of pain, inflammation and fever

Question 7

Some anti-inflammatories inhibit the COX enzyme non-selectively while others specifically target the COX 2
enzyme. What are 4 that are non-specific?

Answer 7

1. Aspirin
2. Ibuprofen
3. Indomethicin
4. Diclofenac