Pain Flashcards

1
Q

What’s chronic pain

A

Pain greater than 12weeks

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2
Q

Depression is a Common comorbidity with chronic pain. True or false?

A

True

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3
Q

What’s primary chronic pain

A

No clear underlying condition

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4
Q

WHO pain ladder

A

See photo

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5
Q

What drug is useful in musculoskeletal pain

A

Nsaids, aspirin and PCM

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6
Q

List drugs used in sickle cell disease

A

Paracetamol and Nsaids, codeine and dihydrocodeine

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7
Q

Drugs used in severe crisis in sickle cell disease

A

Morphine or diamorphine may be needed

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8
Q

Drugs to avoid in sickle cell disease

A

Pethidine because it can cause seizure

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9
Q

Dental pain and orofacial pain tx

A

NSAIDs ( Ibuprofen, Aspirin, Diclofenac) use pcm temporary
Benzydamine mouthwash/spray can be used
Diazepam a muscle relaxant and Anxiolytics used short term

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10
Q

Dysmenorrhoea tx

A

Antiemetic to prevent vomiting
Pcm and NSAID used to provide relief
Oral contraceptive can be used to prevent pain associated with ovulatory cycles

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11
Q

A non-opiod analgesic used to tx headache, musculoskeletal pain , dysmenorrhoea and pyrexia is ….

A

Aspirin

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12
Q

State what to do to prevent GI problems associated with aspirin

A

Take dose after food , enteric coated preps have slow onset of action and therefore unsuitable

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13
Q

Aspirin interacts with…

A

Other drugs especially warfarin which is a special hazard

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14
Q

What drug can be used for pain not responding to non opiod analgesic but has more side effects

A

Nefopam

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15
Q

Indication of NSAID

A

Chronic disease accompanied by pain and inflammation
Short tx of mild -moderate pain but PCM more preferable esp in elderly
Suitable for dysmenorrhoea
Pain caused by secondary bone tumour
Use for post operative analgesia

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16
Q

What drug is preferred over NSAIDs for patients with high risk of G.I side-effects

A

Cyclo-oxygenase 2

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17
Q

Facts about caffeine

A

It is a weak stimulant and enhances analgesic effect

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18
Q

Facts about Opiods analgesic

A

To relief moderate- severe pain of visceral origin
Repeated used may cause dependence and tolerance

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19
Q

Caution with opiod analgesic

A

Caution in impaired respiratory function, asthma, hypotension, MG, shock, convulsive disorder

20
Q

Opiod analgesic should be avoided in…

21
Q

Some opiod side effects

A

Respiratory depression- reversed by naloxone or artificial ventilation
Overdose can cause coma, Respiratory depression and pinpoint pupils

22
Q

Other side effects of opoid

A

Constipation
Dry mouth
N and V
Biliary spasm
Drowsiness
LT use - hypogonadism and adrenal insufficiency
Larger doses- muscle rigidity, hypotension, Respiratory depression

23
Q

Pt and carer advice for opoids

A

Drowsiness, may affect driving or skilled task

24
Q

Facts about morphine as a strong opiod

A

Most valuable opiod analgesic for severe pain despite causing N and V
Confers euphoria and a state of detachment in addition to pain relief
Given every 4hrs
Every 12- 24hrs as MR prep

25
Facts about Buprenorphine
Has both opiod agonist and antagonist properties May ppt withdrawal symptoms Abuse potential and may cause dependent Longer duration of action than morphine Effective sublingually for 6- 8hours Compared to other opoids , it's effects are only partially reversed by nalaxone
26
Patients and carer advice on the use of buprenorphine patches
Apply patch to dry, non irritated, non hairy skin on upper torso or outer arm Avoid heat and sauna as they can increase absorption Remove after 72hrs/ 96hrs/ 7days Avoid same area for atleast 3 weeks Remove if breathing difficulties, drowsiness, confusion or dizziness
27
Examples of patch applied for 7days
Prenotrix, hapoctasin , bupeaze, buplast and relevtec
28
State patch applied for 6 days
Transtec
29
Which buprenorphine patch that is applied weekly
Butec Butrans Reletrans Sevodyne Panitaz Bupramyl
30
Buprenorphine patch applied 4days/96hrs
Bupeaze Buplast Relevtec Transtec
31
Buprenorphine patches applied for 3days/72hrs
Prenotrix Hapoctasin
32
Facts about methadone
Less sedating than morphine Should not be administered more than BD to prevent risk of overdose and accumulation Pt who miss 3 or more days are at risk of OD due to tolerance , reducing dose
33
What's Oxycodone used for
Pain control in palliative care
34
Facts about pethidine
Less constipating than morphine Prompt but short lasting analgesia
35
Facts about Tramadol
Analgesia by opiod effect and enhancement of serotogenic and adrenergic pathway
36
Drugs used to tx neuropathic pain
Amitriptyline, nortriptyline, pregabalin, gabapentine and tramadol Plasters can be used Capsaicin cream- burning sensation can occur during initial tx and limit use
37
Tx of acute Migraine
Tx guided by response and Severity of the attacks Aspirin , soluble pcm effective Offer 5HT1 receptor agonist if above meds ineffective Antiemetic may be required Excess use of Migraine medication can cause over use headache
38
What medication is licensed specifically for Migraine attacks
Tofenamic acid
39
Other drugs licenced for Migraine attacks
Diclofenac, potassium, flurbiprofen and Ibuprofen
40
A 5HT1 agonist used to tx cluster headaches is
Zolmitriptan and sumatriptan
41
List the type of Migraine Triptans not indicated for
Hemiplegic, basillar or opthalmoplegic Migraine
42
An example of ergot alkaloid use to tx Migraine
Ergotamine tartrate Use to manage cluster headaches
43
An antiemetic used in Migraine that promote gastric emptying and normal peristalsis is known as
Domperidone and Metoclopramide
44
List examples of medication used in Migraine prophylaxis
Beta blockers eg propranolol, atenolol, metoprolol, nadolol and timolol TCAs Gabapentine Topimirate Sodium valproate Pizotifen (may cause WG) Botulinum toxin type A( chronic migranes in adult)
45
Drugs used to tx cluster headaches
Sumatriptans by SC injection Sumatriptan nasal spray or Zolmitriptan (unlicensed) if injection is unsuitable 100% Oxygen at a rate of 10-15L/min for 10-20 mins is useful in aborting attack
46
Drugs used for prophylaxis of cluster headache
Attacks last greater than 3weeks Can't be treated effectively Verapamil or lithium ( unlicensed) Prednisone ( short term) Ergotamine tartate
47