Hormone responsive malignancy Flashcards
What’s the most common form of malignancy in women
Breast cancer
Risk factors for Breast cancer
Age
Early onset menstruation, late menopause, family hx , oral contraceptives and post menopausal (HRT)
Management of Breast cancer
Surgery, Radiotherapy, drug therapy or combination of these
State how to treat early and locally advanced BC
Surgery, Radiotherapy or drug tx
State when to use tamoxifen in early and locally advanced BC
Tamoxifen is given after surgery alone or with other chemo medicines
State what to give women who decline chemotherapy in BC
Goserelin
State other drugs use in early and locally advanced BC
Aromatase inhibitor such as anastozole and letrozole
What’s the first line tx for advanced BC
Endocrine therapy
Other tx used in advanced BC
Aromatase inhibitors ( anastrazole, letrozole and exemestane ) offered to patient with no hx of endocrine therapy or in previously treated with tamoxifen
