Pain Flashcards
Nociceptive Pain
results from injury to tissues
called somatic or visceral pain
Responds to opioids, NSAIDs, acetaminophen depending on tissue type
Neuropathic pain
results from injury to peripheral nerves
responds poorly to opioids
Non pharamlogical ways for pain management
hot/cold repositioning message distraction acupuncture spiritual practices TENS
Opioid recepters
Mu
Kappa
Delta
Mu
2 types
- brain, spinal chord, peripheral nervous system
- produces analgesia and sedation
Kappa
brain, spinal chord, PNS
produces analgesia and sedation
Delta
located in the brain and PNS
Analgesia, antidepressant effects
Morphine
binds to Mu and Kappa receptors to produce analgesia
Caffeine
used to enhance the distribution and absorption of the analgesic
relief of head aches (vasoconstrict and decrease intracranial pressure)
Tolerance
increasing doses to obtain same response
Addiction
the continued used of a substance despite its negative health and social consequences
Physical dependence
people with this experience highly uncomfortable symptoms that make them want to continue to use them
Meds used to “get off”
methadone, buprenophine suboxone
uses different receptors
Prostaglandins and Cox 1 and 2
promote inflammation for healing, but cause pain and fever
cox 1: supports blood clotting and protects the lining of the stomach
NSAIDs and COX
NSAIDs block the COX enzymes and reduce prostaglandins throughout the body
What to assess with acetominophine
liver function
What to assess with NSAIDs
GI bleeding
lab values to check prior to admin of NSAIDs are…
eGFR, Creatinine
When to go to PRN meds
when pain is greater than 4/10
ASA side effects
gastric ulcers
bleeding
renal failure
Side effect occurring in children taking ASA
Reyes syndrome
Narcan
opioid antagonist
Migraine tx
begins with acetaminophen or NSAIDs
then triptans
then alkaloids
Triptans
quiets down overactive brain nerves
Sumatriptan
people are more at risk of myocardial infarction
Local anesthetics
produce a rapid loss of sensation to a limited part of the body by blocking the entry of sodium ions into neurons by blocking sodium ion channels