cardiac Flashcards
beta adrenergic vs beta blockers
BA: heart is failing, increase contractility
blocker: heart is working too hard, decrease contractility
vasodilators indications
HTN, HF
Vasodilators MOA
smooth muscle relaxation
dilates peripheral BVs
reduces reload and afterload
Cardiac glycosides indications
HF
stabilize dysrhythmias
cardiac glycosides (+) vs (-)
(+) inotrope: increase contractility
(-) chronotrope: slows HR
cardiac glycosides MOA
blocks sodium potassium pump
HTN is life threatening when diastolic is over…
120 mmHg
management of hypertensive emergency
administer fast acting vasodilators
Nitroprusside sodium
Nitroprusside sodium MOA
(for HTN emergency)
Donates nitric oxide
vasodilator
L vs R sided HF
L: blood cant pump into vasculature, backs up in pulmonary veins, elevated pulmonary pressure and pulmonary edema
R: RV cant pump blood to pulmonary artery, blood backs up into periphery
R sided HF S/S
Systemic HTN Hepatosplenomegaly ] Peripheral edema Ascites Neck vein distension
L sided HF S/S
SOB Tachypnea >60 Orthopnea cough, hoarseness cyanosis wheezing, grunting
How does the body naturally respond to decreased CO?
Increased HR
Increased BP
Increased blood volume
(retains salts and fluids)
What classes of meds are used to suppress body’s response to decreased CO?
ACE inhibitors ARBs Vasodilators Diuretics Beta Blockers
What drug classes can be used to treat HF?
Cardiac glycosides
beta blockers
ace inhibitors
ARBS
CCB
Diuretics
digitalis toxicity
toxic drug effects from administration of digoxin
Digitalis toxicity S\S
halos/rings of light in vision, yellow/green vision SOB Arrhythmia N/V diarrhea anorexia headache dizziness
What do we need to do before administering digoxin?
Assess EF
monitor apical pulse for 60 secs (withhold if HR is <60 bpm)
High risk for digitalis toxicity
Kidney failure, using diuretics
Tx of digitalis toxicity
digibind - digoxin specific antibiodies
how to assess for digitalis toxicity
blood test
Healthy EF
<60% assessed with echocardiogram