cardiac Flashcards

1
Q

beta adrenergic vs beta blockers

A

BA: heart is failing, increase contractility
blocker: heart is working too hard, decrease contractility

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2
Q

vasodilators indications

A

HTN, HF

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3
Q

Vasodilators MOA

A

smooth muscle relaxation
dilates peripheral BVs
reduces reload and afterload

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4
Q

Cardiac glycosides indications

A

HF

stabilize dysrhythmias

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5
Q

cardiac glycosides (+) vs (-)

A

(+) inotrope: increase contractility

(-) chronotrope: slows HR

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6
Q

cardiac glycosides MOA

A

blocks sodium potassium pump

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7
Q

HTN is life threatening when diastolic is over…

A

120 mmHg

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8
Q

management of hypertensive emergency

A

administer fast acting vasodilators

Nitroprusside sodium

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9
Q

Nitroprusside sodium MOA

A

(for HTN emergency)

Donates nitric oxide

vasodilator

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10
Q

L vs R sided HF

A

L: blood cant pump into vasculature, backs up in pulmonary veins, elevated pulmonary pressure and pulmonary edema

R: RV cant pump blood to pulmonary artery, blood backs up into periphery

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11
Q

R sided HF S/S

A
Systemic HTN
Hepatosplenomegaly ]
Peripheral edema
Ascites
Neck vein distension
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12
Q

L sided HF S/S

A
SOB
Tachypnea >60
Orthopnea
cough, hoarseness
cyanosis
wheezing, grunting
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13
Q

How does the body naturally respond to decreased CO?

A

Increased HR

Increased BP

Increased blood volume

(retains salts and fluids)

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14
Q

What classes of meds are used to suppress body’s response to decreased CO?

A
ACE inhibitors
ARBs 
Vasodilators
Diuretics
Beta Blockers
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15
Q

What drug classes can be used to treat HF?

A

Cardiac glycosides

beta blockers

ace inhibitors

ARBS

CCB

Diuretics

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16
Q

digitalis toxicity

A

toxic drug effects from administration of digoxin

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17
Q

Digitalis toxicity S\S

A
halos/rings of light in vision, yellow/green vision
SOB
Arrhythmia
N/V
diarrhea
anorexia
headache
dizziness
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18
Q

What do we need to do before administering digoxin?

A

Assess EF

monitor apical pulse for 60 secs (withhold if HR is <60 bpm)

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19
Q

High risk for digitalis toxicity

A

Kidney failure, using diuretics

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20
Q

Tx of digitalis toxicity

A

digibind - digoxin specific antibiodies

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21
Q

how to assess for digitalis toxicity

A

blood test

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22
Q

Healthy EF

A

<60% assessed with echocardiogram

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23
Q

What to assess before giving cardiac meds

24
Q

MI tx goals

A
restore blood supply to heart
reduce myocardial O2 demand
control dysrhythmias
reduce post-MI mortality
manage pain and anxiety
25
Meds to restore blood supply to heart
Thrombolytics | organic nitrates
26
Meds to reduce myocardial O2 demand
beta blockers
27
Meds to control MI-associated dysrhythmias
Beta blockers | CCB
28
Meds to reduce post-MI mortality
ASA | ACE inhibitors
29
Meds to manage MI pain and anxiety
Analgesics
30
Thrombolytics MOA
stimulates formation of plasmin to break down fibrin (dissolves clots)
31
Assessment during thrombolytic therapy
VS | Neurological status
32
Organic nitrates example
Nitroglycerin
33
Organic nitrates MOA
donates nitric oxide (vasodilator)
34
Organic Nitrates adverse affects
headache, dizziness, orthostatic hypotension, nausea
35
Bradykinin
vasodilator that increases permeability and causes inflammation
36
ACE inhibitors adverse affects
``` cough (no breakdown of bradykinin) hypotension fatigue dizziness headache ```
37
ARBS adverse effects
hypotension dizziness hyperkalemia headaches
38
beta blockers adverse effects
bradycardia hypotension bronchospasm hypoglycemia
39
vasodilators adverse effects
hypotension reflex tachycardia fluid retention
40
Diuretics MOA
decrease sodium reabsorption
41
Diuretics adverse affects
dizziness headache dehydration
42
Cardiac glycosides adverse affects
``` malaise SOB N/V headache, dizziness yellow/green tint, halos bradycardia ```
43
ex of cardiac glucosides
digoxin
44
Diuretics example
furosemide (Lasix)
45
Anticoagulant
inhibits coagulation cascade | prevents clotting
46
Antiplatelet
reduces tendency for platelets to stick together and form a clot
47
Prothrombin time (PT) test
measures how long it takes blood to clot via extrinsic pathway
48
Activated partial thromboplastin clotting time (aPTT) test
measures how long it takes blood to clot via the intrinsic pathway
49
international normalized (INR) test
ensure that PT test results are standardized and accurate
50
intrinsic clotting pathway
activated by contact with damaged BVs
51
Extrinsic clotting pathway
activated by tissue factors released after external damage
52
food to avoid taking when on anticoagulants
Vit K rich foods
53
Natural anticoagulents
turmeric ginger cayenne peppers
54
fluid restriction for HF is
1.5-2L/day
55
when to report weight gain
over 2 kg over 3 days