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NURS 200 > Nursing Therapeutics > Flashcards

Nursing Therapeutics Flashcards

1
Q

Therapy

A

the tx of the disease or disorders as by some remedial, rehabilitating or curative process

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2
Q

Anthropometry

A

height and weight of the person

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3
Q

Considerations around weight

A

done daily @ same time (morning)

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4
Q

Serum proteins

  • Biochemical analysis -
A

nutritional status, liver function

affects level of proteins that liver produces, blood loss

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5
Q

Albumin

  • Biochemical analysis -
A

most common serum protein

longest half life

good snap shot of a person’s nutritional status

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6
Q

Transferrin

  • Biochemical Analysis -
A

protein that transports iron, body increases transferrin if iron deficiency

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7
Q

Transthyretin and retinol binding protein

A

respond to changes to nutrition quickly, affected by many factors

not best lab test to trend

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8
Q

C reactive protein

A

indicator of infection and inflammation

source of metabolic stress

leads to increased nutrition

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9
Q

Usual/ideal body weight

A

provides an estimate of what a person should weigh and rapid weight gain would indicate fluid shifts

usual is more affective than ideal body weight for changes in obese, underweight, or overweight

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10
Q

Therapeutic index

A

measure of the safety of the drug ratio of the lethal dose of a drug and the minimum dose at which a therapeutic affect occurs

narrow: 1-2; difference b/w lethal dose and therapeutic dose is small
- more critical to assess -

Large: 4-5; difference is large

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11
Q

Potency

A

relative amount of a drug required (in comparison to other drugs of the same class) to produce a desired response

Higher potency = lower dose

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12
Q

Efficacy

A

measure the amount of the magnitude of maximal response in the patient that can be produced by a particular drug

lower dose (does not equal) decreased side effects

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13
Q

Drug actions

A

mechanism of drug actions in living tissues

  1. receptor interactions
  2. enzyme interactions
  3. nonspecific interactions
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14
Q

Drug effect

A

the physiologic reaction of the body to the drug

potency and therapeutic index

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15
Q

acute therapy

A

ICU or trauma rooms

ex. high risk meds in controlled environments

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16
Q

Maintenance therapy

A

Chronic disease management

ex. HTN, DM II meds

17
Q

Supplemental therapy

A

TPN, insulin

18
Q

Palliative therapy

A

care vs cure

ex. narcotics, anti-anxiety

19
Q

supportive therapy

A

supports physiological needs

ex. fluids and electrolytes, blood products and oxygen

20
Q

Prophylactic therapy

A

ABX for asplenic pts

21
Q

Empiric therapy

A

based on precedence rather than research

ex. use of acetaminophen in a fever of unknown origin

22
Q

Monitoring Pharmacotherapy carefully

A
  • therapeutic index
  • drug concentration
  • pts condition
  • tolerance and dependence
  • interactions
  • side effects/adverse drug affects
23
Q

Pharmacologic rxns

A

it works too good

24
Q

Idiosyncratic rxns

A

particular to the pt, but not a true allergy or a pharmacologic rxn

25
Q

Allergic rxn

A

pts immune system decides to treat a drug as a dangerous character and overreacts

26
Q

Dose dependent effect

A

some adverse drug rxns are classified as side affects

expected, well-known rxns that result in little or no change in pt management (predicable)

effects intensity and occurrence are related to size of dose

27
Q

Additive affect

A

2 drugs are given together and they add to each of their effectiveness

28
Q

Synergistic effect

A

involves magnification of magnitude

equals more than they normally would on their own

29
Q

Antagonistic effect

A

one drug cancels the other one out or minimize other side affects

30
Q

Receptor Interaction

A

a molecule where a med binds to initiate its effect

31
Q

Selective Receptor interaction

A

binds with one type of receptor

32
Q

Non-selective receptor interaction

A

binds with several types of receptors

33
Q

Types of receptor interactions

A

Agonist

Partial agonist

Antagonist

34
Q

Agonist

A

drug produced response that mimics effect of the endogenous regulatory molecule

35
Q

Partial Agonist

A

med that produces weaker/lower effective response than agonist

36
Q

Antagonist

A

Blocks receptor

  1. competitive: compete with the agonist for receptor sites
  2. Non-competitive: binds with receptor sites and blocks the affect of the agonist
  3. Functional: does not bind to receptor, works against the antagonist to slow drug absorption or speed up metabolism or excretion enhancing the removal of the drug
37
Q

Enzyme interaction

A

enzymes are inhibited where it binds to the drug instead of the target cell

38
Q

Enzyme

A

proteins that catalyze almost every cellular biochemical reaction

39
Q

Nonspecific interactions

A

Doesn’t involve receptors or enzymes instead…cell membranes or metabolic processes are the biochemical target

NURS 200 (18 decks)

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