Page 35 Flashcards
Which geometry does E2 elimination most often occur in?
A: Anti periplanar geometry.
Why is anti periplanar geometry preferred in E2 reactions?
A: It allows the molecule to react in a lower-energy staggered conformation.
What is the geometry of a syn periplanar arrangement?
A: A syn periplanar arrangement has an eclipsed conformation where the electron-rich groups are close together.
Why is anti periplanar geometry more reactive than syn periplanar?
A: Anti periplanar reduces steric hindrance and electron repulsion, facilitating a more favorable transition state.
How are the base and leaving group positioned in anti periplanar geometry?
A: They are positioned opposite to each other, leading to a staggered conformation.
What happens to the molecule in a syn periplanar arrangement?
A: The molecule reacts in an eclipsed conformation, which is higher in energy and less favorable.
In which conformation are two electron-rich groups closer together: anti or syn periplanar?
A: In syn periplanar geometry, the electron-rich groups are closer together.
What is the impact of the anti periplanar arrangement on transition state energy?
A: It lowers the energy of the transition state, making the reaction proceed more efficiently.
What does the anti periplanar arrangement ensure about orbital overlap?
A: It ensures proper orbital alignment for the elimination to occur.
How does the syn periplanar geometry affect reaction rate compared to anti periplanar?
A: Syn periplanar geometry slows the reaction rate due to its higher energy and unfavorable eclipsed conformation.
