Page 23 Flashcards
Why does the E2 reaction rate increase with increasing alkyl substitution?
A: Alkyl substituents stabilize the transition state of the reaction by stabilizing the partially formed double bond, which lowers the activation energy (E_a).
Flashcard 2
Q: What happens in the transition state of an E2 reaction?
A: The double bond is partially formed, and the proton is being removed by the base while the leaving group departs simultaneously.
How do alkyl groups stabilize the transition state in an E2 reaction?
A: Alkyl groups donate electron density through hyperconjugation, stabilizing the partially formed double bond.
What is the effect of stabilizing the transition state in E2 mechanisms?
A: It reduces the energy barrier for the reaction, increasing the rate of the reaction.
What is shown in the diagram?
A: The transition state of an E2 reaction with an alkoxide ( -OR ) as the base. The proton is being abstracted, the leaving group departs, and the double bond begins to form.
