Paediatrics prescription

Question 2

Considerations in paediatric prescribing

Answer 2

1. Age and DoB
2. Current body weight (check appropraiteness of written BW)
3. Body surface area
4. Drug allergy
5. G6PD status
6. Current drug profile review: avoid overdose, D-D interaction, Therapeutic duplications…etc
7. L/RFT: eGFR with bedside Schwartz Formula (Not using Cockcroft and Gault for adults)
8. Decide dose regimen: dose, frequency, duration, route…etc; Dose per unit mass/ BSA (mg/kg or mg/m^2)
9. Therapeutic drug monitoring: clinical resolution, side effect (esp. Vancomycin, Digoxin, Lithium… with narrow therapeutic index)
10. Side effects: Nephrotoxicity, Hepatotoxicity, D-D interaction, Drug- Disease interaction
11. Chemical compatibility

Question 3

Body surface area calculation

Answer 3

Question 4

Examples of imcompatible drug pairs

Methods to check drug incompatibility

Answer 4

Refer to reliable references
Consult clinical pharmacist