Paediatric oncology Flashcards
Childhood malignancy
Risk factors
Clinical presentation
General Ix
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Leukaemia
Classification
General clinical features
Approach to dx
Acute leukaemia
S/S
Dx
Ix
Acute leukaemia
Standard Ix
Acute leukaemia
General Mx
Tx phases
ALL
Peak age incidence
Pathogenesis
ALL
Clinical features
B vs T cell markers
ALL
Ix features
ALL
Dx
Ddx
ALL
Pre-tx evaluations
ALL
Treatment
Supportive therapy
ALL
Post-remission therapy
Monitoring
ALL
Poor prognostic factors
Neutropenic fever
Definition
Pathogenesis
Pathogens
Neutropenic fever
Mx
TLS
Pathogenesis
Risk factors
TLS
Mx
TLS
Prevention
Hyperleukocytosis and leukostasis
Definition
Causes
S/S
Mx
Lymphoma
Types
Causes/ Risk factors
Lymphoma
Classification
High grade vs low grade NHL
Lymphoma
Clinical presentation
Cx
Lymphoma
P/E
Lymphoma
Ix
NHL
Staging
Mx
Paediatric brain tumours
Common site of involvement
Classification
Top 4 types
Brain tumour
Clinical presentation
Brain tumour
Ix
Gliomas
Types
Classification
Mx
Prognosis
PNETs
Most common type
Site
Mx
GCT
Types
Location
Pineal gland tumor
Types
S/S
Dx
Mx
Mx:
- surgical resection dangerous → biopsy only
- chemo or radiotherapy (mainstay)
- endoscopic 3rd ventriculostomy (ETV):
puncturing of floor of 3rd ventricle → drainage of hydrocephalus
GCT
Tumor markersA
Neuroblastoma
Epidemiology
Types
Associated diseases
Neuroblastoma
S/S
Neuroblastoma
Ix
Neuroblastoma
Staging
Neuroblastoma
Tx
Nephroblastoma
Epigemiology
Pathogenesis
Clinical presentation
Nephroblastoma
Ix
Classification
Nephroblastoma
Tx
Hepatoblastoma
Epidemiology
Associated disease
Typical site
Hepatoblastoma
Clinical presentation
Ix
Hepatoblastoma
Staging
Mx
Rhabdomyosarcoma
Types
Site of involvement
Associated disease
Rhabdosorcoma
Clinical presentation
Rhabdosarcoma
Ix
Dx
Mx
Osteosarcoma
Risk factors
Site
Osteosarcoma
Clinical presentation
Osteosarcoma
Ix
Staging
Osteosarcoma
Mx
Langerhans cell histiocytosis
Epidemiology
Pathogenesis
Langerhans cell histiocytosis
Clinical features
LCH
Dx
LCH
Mx