oxygen

Question 1

Classification

O₂

Answer 1

naturally occuring atmospheric gas

Question 2

INDICATIONs

O₂

Answer 2

• Prevent/treat hypoxemia
• Acute ischemic chest pain
• Limits the size of myocardial infarction
• Resp distress
• Decreases hemoglobin/oxygen carrying capacity
• Treatment of prophylaxis for decrease in atmospheric pressure (decreases PO2) for air transport
• decreased LOC (any cause)

Question 3

CONTRAINDICATIONs

O₂

Answer 3

*NO absolute contraindications

Poisoning from the herbicide paraquat // diquat // pt w/ tx chemotherapy (e.g bleomycin) may result in serious pulmonary complications (eg, oxygen toxicity and pulmonary fibrosis)

*Use with caution in COPD - watch for signs of hypoventilation

Question 4

Pharmacodynamic

O₂

Answer 4

• increases PO2
• reverses hypoxemia
• oxidizes glucose to produce ATP (energy source)

Question 5

Pharmacokinetics

O₂

Answer 5

onset - immediate
peak - < 1 min
duration - 2 mins

Question 6

Dosage

O₂

Answer 6

High FiO2 for patients with signs and symptoms of cardiac or respiratory distress, failure or decreased O2 carrying capacity

consider lower FiO2 in the newborn and head inj pt

Question 7

Warnings // Precautions

O₂

Answer 7

neonates: prolonged exposure to high PO2 may cause blindness

Question 8

ADVERSE EFFECTs

O₂

Answer 8

none with short term use

secondary brain injury occurs largely as a result of oxygen-free radicals, hence the rationale for the current trend to limit FiO2 in the head injured patient