morphine Flashcards
1
Q
Class
morphine
A
opioid analgesic
2
Q
INDICATIONS
morphine
A
PCP - analgesia
ACP - symptom relief in palliative (end-of-life) - pain or SOB
CCP - analgesia
*PCP requires scope expansion training
3
Q
CONTRAINDICATIONS
morphine
A
- hypersensitivity to morphine or other opioid analgesics
4
Q
DOSAGE - ADULT
morphine
A
ACP - symptom relief in palliative (end-of-life) - pain or SOB
0.1mg/kg SC or 2.5-5mg SC
repeat q 10-30mins as required based on BP (>100 mmHg) or per care team plan
☎️ cliniCALL/palliative care time consult required
5
Q
Pharmacodynamics
morphine
A
- acts on opiod receptors (mu receptors) in the CNS to produce analgesia, euphoria and sedation
- interaction w/ receptors in spinal cord - depresses pain transmission
- produces venodilation
- reduces cardiac preload
6
Q
Pharmacokinetics
morphine
A
parenteral
onset - 5-20mins
peak - 60mins
duration - 3-4hrs
7
Q
Warning // Precautions
morphine
A
- ACETAMINOPHEN is the leading cause of liver injury in Canada
@RISK PTs w/
* preexisting liver disease
* chronic users of acetaminophen
* pediatrics
- common in OTC medications - FULL rx hx required
8
Q
ADVERSE EFFECTs
morphine
A
- lightheadedness
- dizziness
- sedation
- agitation
- respiratory depression, apnea
- profound hypotension
- nausea // vomitng
9
Q
Brand Names
morphine
A
MS-Contin
Roxanol
Kadian
MSiR
