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Infecto > Oxazolidinonas > Flashcards

Oxazolidinonas Flashcards

1
Q

Mecanismo de accion de las oxazolidinonas

A

Inhiben la sintesis de proteinas uniendose a la subunidad ribosomal 50s

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2
Q

VA de las oxazolidinonas

A

EV

VO (100%)

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3
Q

VE de las oxazolidinonas

A

60 %H

40% R

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4
Q

Cobertura de las oxazolidinonas

A

MRSA
VRSA
Estreptococo
VRE

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5
Q

Cuales son las oxazolidinonas

A

Linezolid

Tedizolid

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6
Q

Efectos adversos de las oxazolidinonas

A 
Se dan 14 dias despues
Sindrome serotoninergico
Inhiben la MAO
Mielotoxicidad
Neuritis opitca
Hiperpigmentacion lingual
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7
Q

Las oxazolidinonas se utilizan en el embarazo?

A

No

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8
Q

Las oxazolidinonas atraviesan la BHE?

A

No

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9
Q

Contraindicaciones de las oxazolidinonas

A 
Meningitis
Endocarditis
Quimioterapia
IVU
Antidepresivos ISRS
No usar en neumonia cuando se sospeche de TB
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10
Q

Indicaciones de las oxazolidinonas

A

NAV/Nosocomial
IPBT
Osteomielitis
Diarrea asociada a ATB (resistente a vancomicina)

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11
Q

Las oxazolidinonas alcanzan buena concentracion sanguinea?

A

No

No esteriliza LCR

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12
Q

Las oxazolidinonas tienen buena concentracion bronquial?

A

Si

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13
Q

Cual es la oxazolidinonas de menor riesgo serotoninergico?

A

Tedizolid

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Infecto (21 decks)

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