Fosfomicina Flashcards

1
Q

Mecanismo de accion de la fosfomicina

A

Inhiben la sintesis de peptidoglucano al bloquear la enolpiruvato transferasa. Es bactericida.

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2
Q

VA de la fosfomicina

A

VO

EV

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3
Q

VE de la fosfomicina

A

R

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4
Q

Cobertura de la fosfomicina

A
Cocos (+)
MRSA
Estreptococo
NO neumococo
VRE
Bacilos (-)
Pseudomonas
Bacilos aerobios
Anaerobios
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5
Q

Efectos adversos de la fosfomicina

A

Hemorragias
Moniliasis oral/vaginal
Diarrea por ATB

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6
Q

Se puede usar fosfomicina en el embarazo?

A

Si

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7
Q

La fosfomicina atraviesa la BHE?

A

No

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8
Q

Contraindicaciones de la fosfomicina

A

Pielonefritis

Embarazadas con IVU

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9
Q

Indicaciones de la fosfomicina

A

IVU baja no complicada
IVU causada VRE
NO APROBADO EN USA PARA: Osteomielitis ni IPBT

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10
Q

Los bacteroides son resistentes a la fosfomicina?

A

Si

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