Nitrofuranos Flashcards

1
Q

Nombre del nitrofurano

A

Nitrourantoina

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2
Q

Mecanismo de accion de los nitrofuranos

A

Degradan el ADN e inhiben la sintesis proteica. Son bactericidas

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3
Q

Cobertura de los nitrofuranos

A

Bacilos (-)
Pseudomonas
Bacilos aerobios

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4
Q

VA de los nitrofuranos

A

VO

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5
Q

VE de los nitrofuranos

A

R

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6
Q

Efectos adversos de los nitrofuranos

A

Neuropatia periferica
Fibrosis pulmonar
Hemolisis

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7
Q

Los nitrofuranos atraviesan la BHE?

A

No

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8
Q

Los nitrofuranos se utilizan en el embarazo?

A

Si

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9
Q

Contraindicaciones de los nitrofuranos

A

No usar de 1-2 semanas preparto por riesgo hemolisis
IVU por Proteus (pH alcalino inactiva nitrofurantoina)
Neonatos
Deficiencia G6PD

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10
Q

Indicaciones de los nitrofuranos

A

IVU no complicadas

Profilaxis IVU en mujeres

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11
Q

Los nitrofuranos tienen metabolismo hepatico?

A

Si

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